• Search
      • Search Interactions Search Categories
    • Browse
      • Browse Categories Browse Sources
    • Information
      • About Publications Interaction Types & Directionalities Interaction Score & Query Score API Documentation FAQ Known Data Clients News Contact
    • Downloads
      • Data Source Code

GJA1 Gene Record

  • Summary
  • Interactions
  • Claims
  • GJA1 2697

    Alternate Names:

    2697
    GAP JUNCTION PROTEIN ALPHA 1
    GJA1
    AVSD3
    CMDR
    CX43
    EKVP
    EKVP3
    GJAL
    HLHS1
    HSS
    ODDD
    PPKCA
    121014
    4274
    ENSG00000152661
    OTTHUMG00000015479
    Gap junction alpha-1 protein
    T44479

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    Publications:

    Cui et al., 2006, [Changes of tight junction and Cx43 expression in microvessel endothelial cells of mouse lung induced by bleomycin]., Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
    Yeh et al., 2006, Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-day carvedilol treatment., Am. J. Hypertens.
    Fan et al., 2005, [Effects and the mechanism of carvedilol on gap junctional intercellular communication in rat myocardium]., Zhonghua Xin Xue Guan Bing Za Zhi
    Takahashi et al., The preventive effect of green tea on the gap junction intercellular communication in renal epithelial cells treated with a renal carcinogen., Anticancer Res.
    St-Pierre et al., 2003, Neonatal hypothyroidism alters the localization of gap junctional protein connexin 43 in the testis and messenger RNA levels in the epididymis of the rat., Biol. Reprod.
  • LABETALOL   GJA1

    Interaction Score: 1.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16448880


    Sources:
    NCI

  • CARVEDILOL   GJA1

    Interaction Score: 1.72

    Interaction Types & Directionality:
    other/unknown

    Interaction Info:

    PMIDs:
    16448880 16563290


    Sources:
    NCI

  • PROPYLTHIOURACIL   GJA1

    Interaction Score: 1.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12606457


    Sources:
    NCI

  • BLEOMYCIN   GJA1

    Interaction Score: 1.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16600115


    Sources:
    NCI

  • EPIGALOCATECHIN GALLATE   GJA1

    Interaction Score: 0.79

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15736408


    Sources:
    NCI

  • ATENOLOL   GJA1

    Interaction Score: 0.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16448880


    Sources:
    NCI

  • Ensembl: ENSG00000152661

    • Version: 101_38

    Alternate Names:
    GJA1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: GJA1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Takahashi et al., The preventive effect of green tea on the gap junction intercellular communication in renal epithelial cells treated with a renal carcinogen., Anticancer Res.
    Yeh et al., 2006, Reduced expression of endothelial connexins 43 and 37 in hypertensive rats is rectified after 7-day carvedilol treatment., Am. J. Hypertens.
    Zhang et al., 2006, Acetylcholine inhibits the hypoxia-induced reduction of connexin43 protein in rat cardiomyocytes., J. Pharmacol. Sci.

  • TTD: Gap junction alpha-1 protein

    • Version: 2020.06.01

    Alternate Names:
    GJA1 TTD Gene Abbreviation
    T44479 TTD Target ID

    Gene Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21