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GLI1 Gene Record

  • Summary
  • Interactions
  • Claims
  • GLI1 2735 Clinically Actionable

    Alternate Names:

    2735
    GLI FAMILY ZINC FINGER 1
    GLI1
    GLI
    165220
    4317
    ENSG00000111087
    OTTHUMG00000167332
    Zinc finger protein GLI1
    T40890
    PAPA8
    PPD1
    P08151

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    CLINICALLY ACTIONABLE
    TRANSCRIPTION FACTOR

    Publications:

    Arai MA et al., 2015, Hedgehog inhibitors from Artocarpus communis and Hyptis suaveolens., Bioorg Med Chem
    Arai MA et al., 2008, Hedgehog/GLI-mediated transcriptional inhibitors from Zizyphus cambodiana., Bioorg Med Chem
    Yoneyama T et al., 2015, Hedgehog inhibitors from Withania somnifera., Bioorg Med Chem Lett
  • CHEMBL1934585   GLI1

    Interaction Score: 20.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26169123


    Sources:
    DTC

  • COLUBRINIC ACID   GLI1

    Interaction Score: 20.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18842418


    Sources:
    DTC

  • CHEMBL512307   GLI1

    Interaction Score: 20.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26178912


    Sources:
    DTC

  • CHEMBL471694   GLI1

    Interaction Score: 20.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26178912


    Sources:
    DTC

  • BETULINIC ACID   GLI1

    Interaction Score: 5.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18842418


    Sources:
    DTC

  • WITHAFERIN A   GLI1

    Interaction Score: 1.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26169123


    Sources:
    DTC

  • Ensembl: ENSG00000111087

    • Version: 101_38

    Alternate Names:
    GLI1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: GLI1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Goyette et al., 2000, Regulation of gli activity by all-trans retinoic acid in mouse keratinocytes., Cancer Res.

  • DTC: GLI1

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Arai MA et al., 2008, Hedgehog/GLI-mediated transcriptional inhibitors from Zizyphus cambodiana., Bioorg Med Chem
    Arai MA et al., 2015, Hedgehog inhibitors from Artocarpus communis and Hyptis suaveolens., Bioorg Med Chem
    Yoneyama T et al., 2015, Hedgehog inhibitors from Withania somnifera., Bioorg Med Chem Lett

  • Tempus: GLI1

    • Version: 11-November-2018

    Alternate Names:
    GLI1 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • TTD: Zinc finger protein GLI1

    • Version: 2020.06.01

    Alternate Names:
    Gli1 TTD Gene Abbreviation
    T40890 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: GLI1

    • Version: 01-February-2022

    Alternate Names:
    Zinc finger protein GLI1 Gene Name
    P08151 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSCRIPTION FACTOR

    Publications:

  • FoundationOneGenes: GLI1

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21