• GLRA3 8001 Druggable Genome

    Alternate Names:

    8001
    GLYCINE RECEPTOR ALPHA 3
    GLRA3
    600421
    4328
    ENSG00000145451
    OTTHUMG00000149816
    O75311
    GLRA3_HUMAN
    GLYCINE RECEPTOR SUBUNIT ALPHA-3
    GLYCINE RECEPTOR ALPHA-3 CHAIN PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:O75311]
    425
    glycine receptor α3 subunit
    NM_006529
    NP_006520

    Gene Info:

    Interpro Type Domain
    Interpro Acc IPR006201
    Human Readable Name ION CHANNEL
    Interpro Type Family
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Neurotransmitter-gated ion-channel ligand-binding
    Uniprot Status Swiss-Prot
    Interpro Name Neurotransmitter-gated ion-channel
    Interpro Short Name Neur_chan_lig-bd
    Interpro Short Name Neur_channel
    Interpro Acc IPR006202
    Uniprot Evidence 1: Evidence at protein level
    Target Subclass Channels
    Target Subclass Ligand_gated_ion_channels
    Target Subclass cys-loop
    Transmembrane Helix Count 4
    Target Main Class Receptors
    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name Glycine receptors
    GuideToPharmacology Gene Category ID 73
    (3 More Sources)

    Gene Categories: Category Details

    ION CHANNEL
    DRUGGABLE GENOME
  • Interaction Score: 2.28

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 2.28

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Antagonist

    PMIDs:
    None found


  • Interaction Score: 2.28

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 1.19

    Interaction Types & Directionality:
    antagonist (inhibitory)
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction block is weaker when β subunit is co-expressed
    Endogenous Drug? False

  • Interaction Score: 0.91

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.83

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.17

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    GLRA3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    O75311 Uniprot Accession
    8001 Entrez Gene Id
    ENSG00000145451 Ensembl Gene Id

    Gene Info:
    Interpro Type Domain
    Interpro Acc IPR006201
    Human Readable Name ION CHANNEL

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: 01-August-2011

    Alternate Names:
    GLRA3 Gene Symbol
    8001 Entrez Gene Id
    ENSG00000145451 Ensembl Gene Id

    Gene Info:
    Target Subclass Channels
    Target Subclass Ligand_gated_ion_channels
    Target Subclass cys-loop

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    GLRA3 Display Id
    GLYCINE RECEPTOR ALPHA-3 CHAIN PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:O75311] Description
    ENSG00000145451 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    4328 HUGO Gene ID
    4328 HUGO Gene Symbol
    glycine receptor alpha 3 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Glycine receptors
    GuideToPharmacology Gene Category ID 73

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000145451 Gene Symbol
    GLRA3 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Glycine receptor subunit alpha-3 Gene Name
    O75311 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: