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GRIK2 2898 Druggable Genome
Alternate Names:
2898 GLUTAMATE IONOTROPIC RECEPTOR KAINATE TYPE SUBUNIT 2 GRIK2 EAA4 GLR6 GLUK6 GLUR6 GluK2 MRT6 138244 4580 ENSG00000164418 OTTHUMG00000016328 GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2 PRECURSOR (GLUTAMATE RECEPTOR 6) (GLUR-6) (GLUR6) (EXCITATORY AMINO ACID RECEPTOR 4) (EAA4). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13002] Q13002 451 NM_021956 NP_068775 GRIK2_HUMAN KA2 EAA2 GRIK5 Glutamate receptor ionotropic, kainate 5 Excitatory amino acid receptor 2 Glutamate receptor KA-2 GluK5 GluR-6 Glutamate receptor 6 Excitatory amino acid receptor 4 Glutamate receptor ionotropic, kainate 2 GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2 Gene Info:
Human Readable Name DRUGGABLE GENOME GuideToPharmacology Gene Category Name Ionotropic glutamate receptors GuideToPharmacology Gene Category ID 75 Target Subclass Glutamate Target Subclass Ligand_gated_ion_channels Target Subclass Channels Transmembrane Helix Count 3 Target Main Class Receptors Interpro Acc IPR001320 Interpro Short Name Iontro_glu_rcpt Interpro Type Domain Interpro Name Ionotropic glutamate receptor Uniprot Evidence 1: Evidence at protein level Uniprot Status Swiss-Prot Target Class Receptors Target Subclass TC:1.A.10.1 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
ION CHANNEL DRUGGABLE GENOME
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Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name - Novel drug target Established target -
Interaction Score: 1.7
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name - Novel drug target Established target -
Interaction Score: 1.7
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name - Novel drug target Established target -
Interaction Score: 1.7
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Novel drug target Established target Trial Name - -
Interaction Score: 1.55
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name - Novel drug target Established target -
Interaction Score: 1.42
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name - Novel drug target Established target -
Interaction Score: 0.95
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist Direct Interaction yes Novel drug target Established target -
Interaction Score: 0.85
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name - Novel drug target Established target -
Interaction Score: 0.85
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Novel drug target Established target Trial Name - -
Interaction Score: 0.85
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Novel drug target Established target Trial Name - -
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name - Novel drug target Established target -
Interaction Score: 0.53
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist Direct Interaction yes -
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name - Novel drug target Established target -
Interaction Score: 0.46
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Novel drug target Established target Trial Name - -
Interaction Score: 0.1
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist
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- Version: 101_38
Alternate Names:
GRIK2 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 11-September-2012
Alternate Names:
GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2 Uniprot Protein Name GRIK2 Uniprot Gene Name ENSG00000164418 Ensembl Gene Id Gene Info:
Interpro Acc IPR001320 Interpro Short Name Iontro_glu_rcpt Interpro Type Domain Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 26-July-2011
Alternate Names:
GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 2 PRECURSOR (GLUTAMATE RECEPTOR 6) (GLUR-6) (GLUR6) (EXCITATORY AMINO ACID RECEPTOR 4) (EAA4). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13002] Description GRIK2 Display Id ENSG00000164418 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
GRIK2 Gene Symbol GRIK2_HUMAN Uniprot Id Q13002 Uniprot Accession Gene Info:
Target Subclass Glutamate Target Subclass Ligand_gated_ion_channels Target Subclass Channels Publications:
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- Version: January-2014
Alternate Names:
GRIK2 Gene Symbol Gene Info:
Target Class Receptors Target Subclass TC:1.A.10.1 Publications:
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- Version: 29-September-2020
Alternate Names:
4580 HUGO Gene ID 4580 HUGO Gene Symbol glutamate ionotropic receptor kainate type subunit 2 HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name Ionotropic glutamate receptors GuideToPharmacology Gene Category ID 75 Gene Categories:
ION CHANNEL Publications:
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- Version: chembl_23
Alternate Names:
GLUR6 GENE_SYMBOL GRIK2 GENE_SYMBOL Glutamate receptor ionotropic, kainate 2 UNIPROT Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000164418 Gene Symbol GRIK2 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
GRIK2 GENE_SYMBOL GRIK5 GENE_SYMBOL Glutamate receptor ionotropic, kainate 5 UNIPROT Gene Info:
Publications:
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Alternate Names:
Glutamate receptor ionotropic, kainate 2 Gene Name Q13002 UniProt ID Gene Info:
Gene Categories:
ION CHANNEL Publications: