• GRK2 156 Druggable Genome

    Alternate Names:

    156
    G PROTEIN-COUPLED RECEPTOR KINASE 2
    GRK2
    ADRBK1
    BARK1
    BETA-ARK1
    109635
    289
    ENSG00000173020
    OTTHUMG00000167104
    P25098
    ARBK1_HUMAN
    BETA-ADRENERGIC RECEPTOR KINASE 1 (EC 2.7.1.126) (BETA-ARK-1) (G- PROTEIN COUPLED RECEPTOR KINASE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:P25098]
    BETA-ADRENERGIC RECEPTOR KINASE 1
    beta adrenergic receptor kinase 1
    T62548
    NM_001619
    NP_001610
    1466

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Type Domain
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Human Readable Name KINASE
    Interpro Acc IPR002290
    Uniprot Evidence 1: Evidence at protein level
    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name Beta-adrenergic receptor kinases (βARKs)
    GuideToPharmacology Gene Category ID 507
    (4 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    G PROTEIN COUPLED RECEPTOR
    DRUGGABLE GENOME
    ENZYME
    TRANSCRIPTION FACTOR

    Publications:

  • Interaction Score: 4.91

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Inhibition of tubulin phosphorylation by balanol.
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    GRK2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000173020 Ensembl Gene Id
    BETA-ADRENERGIC RECEPTOR KINASE 1 (EC 2.7.1.126) (BETA-ARK-1) (G- PROTEIN COUPLED RECEPTOR KINASE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:P25098] Description
    ADRBK1 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000173020 Ensembl Gene Id
    ARBK1_HUMAN Uniprot Id
    BETA-ADRENERGIC RECEPTOR KINASE 1 Uniprot Protein Name

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    289 HUGO Gene ID
    289 HUGO Gene Symbol
    G protein-coupled receptor kinase 2 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Beta-adrenergic receptor kinases (βARKs)
    GuideToPharmacology Gene Category ID 507

    Gene Categories:
    ENZYME

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000173020 Gene Symbol
    ADRBK1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    156 Gene ID
    BARK1 dGene Synonym
    BETA-ARK1 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    ADRBK1 TTD Gene Abbreviation
    T62548 TTD Target ID

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Beta-adrenergic receptor kinase 1 Gene Name
    P25098 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, G PROTEIN COUPLED RECEPTOR, TRANSCRIPTION FACTOR

    Publications: