• GRK3 157 Druggable Genome

    Alternate Names:

    157
    G PROTEIN-COUPLED RECEPTOR KINASE 3
    GRK3
    ADRBK2
    BARK2
    109636
    290
    ENSG00000100077
    OTTHUMG00000150280
    P35626
    ARBK2_HUMAN
    BETA-ADRENERGIC RECEPTOR KINASE 2
    BETA-ADRENERGIC RECEPTOR KINASE 2 (EC 2.7.1.126) (BETA-ARK-2) (G- PROTEIN COUPLED RECEPTOR KINASE 3). [SOURCE:UNIPROT/SWISSPROT;ACC:P35626]
    beta adrenergic receptor kinase 2
    1467
    NM_005160
    NP_005151

    Gene Info:

    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name KINASE
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Uniprot Status Swiss-Prot
    Interpro Type Domain
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR002290
    Uniprot Evidence 2: Evidence at transcript level
    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name Beta-adrenergic receptor kinases (βARKs)
    GuideToPharmacology Gene Category ID 507
    (3 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • Interaction Score: 4.91

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    GRK3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    157 Entrez Gene Id
    BETA-ADRENERGIC RECEPTOR KINASE 2 Uniprot Protein Name
    P35626 Uniprot Accession

    Gene Info:
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name KINASE
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ADRBK2 Display Id
    ENSG00000100077 Ensembl Gene Id
    BETA-ADRENERGIC RECEPTOR KINASE 2 (EC 2.7.1.126) (BETA-ARK-2) (G- PROTEIN COUPLED RECEPTOR KINASE 3). [SOURCE:UNIPROT/SWISSPROT;ACC:P35626] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    290 HUGO Gene ID
    290 HUGO Gene Symbol
    G protein-coupled receptor kinase 3 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Beta-adrenergic receptor kinases (βARKs)
    GuideToPharmacology Gene Category ID 507

    Gene Categories:
    ENZYME

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000100077 Gene Symbol
    ADRBK2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    157 Gene ID
    BARK2 dGene Synonym
    GRK3 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Beta-adrenergic receptor kinase 2 Gene Name
    P35626 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications: