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GRP Gene Record

  • Summary
  • Interactions
  • Claims
  • GRP 2922 Druggable Genome

    Alternate Names:

    2922
    GASTRIN RELEASING PEPTIDE
    GRP
    BN
    GRP-10
    preproGRP
    proGRP
    137260
    4605
    ENSG00000134443
    OTTHUMG00000132760

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME

    Publications:

    Karlsson et al., 1999, Cytosolic Ca2+ oscillations by gastrin releasing peptide in single HIT-T15 cells., Peptides
    Chandan et al., 1988, Actions of gastrin-releasing peptide and related mammalian and amphibian peptides on ion transport in the porcine proximal jejunum., Regul. Pept.
    Gawin et al., 1993, Effects of gastrin-releasing peptide and analogues on guinea pig nasal mucosal secretion., Am. J. Physiol.
    el-Omar et al., 1996, Marked rebound acid hypersecretion after treatment with ranitidine., Am. J. Gastroenterol.
    de Moura et al., 2001, Aging and gender affect the response of thyrotropin (TSH) to gastrin releasing peptide (GRP) in rats., Life Sci.
    Moura et al., 1999, Interaction between substance P and gastrin-releasing peptide on thyrotropin secretion by rat pituitary in vitro., Braz. J. Med. Biol. Res.
    Yamaguchi et al., 2007, Serum progastrin-releasing peptide levels followed by whole-body positron emission tomography detects early recurrence of small-cell lung cancer., Respirology
    Nishi et al., 1987, Effects of naloxone on basal and vagus nerve-induced secretions of GRP, gastrin, and somatostatin from the isolated perfused rat stomach., Life Sci.
  • THYROTROPIN   GRP

    Interaction Score: 5.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11292067 10464393


    Sources:
    NCI

  • NALOXONE   GRP

    Interaction Score: 1.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2889122


    Sources:
    NCI

  • FUROSEMIDE   GRP

    Interaction Score: 1.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3238049


    Sources:
    NCI

  • RANITIDINE   GRP

    Interaction Score: 1.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8607506


    Sources:
    NCI

  • ALBUMIN HUMAN   GRP

    Interaction Score: 1.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8476064


    Sources:
    NCI

  • NIFEDIPINE   GRP

    Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10465509


    Sources:
    NCI

  • CISPLATIN   GRP

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17207039


    Sources:
    NCI

  • Ensembl: ENSG00000134443

    • Version: 101_38

    Alternate Names:
    GRP Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: GRP

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Karlsson et al., 1999, Cytosolic Ca2+ oscillations by gastrin releasing peptide in single HIT-T15 cells., Peptides
    Chandan et al., 1988, Actions of gastrin-releasing peptide and related mammalian and amphibian peptides on ion transport in the porcine proximal jejunum., Regul. Pept.
    Takagi et al., 1986, Paradoxical effects of gastrin releasing peptide on gastrin release and gastric secretion in the rat., Gastroenterol. Jpn.

  • HingoraniCasas: ENSG00000134443

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000134443 Gene Symbol
    GRP Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21