83933 |
HISTONE DEACETYLASE 10 |
HDAC10 |
HD10 |
608544 |
18128 |
ENSG00000100429 |
OTTHUMG00000044647 |
Q969S8 |
2614 |
T94324 |
NM_032019 |
NP_114408 |
BE0009579 |
Target Subclass | EC:3.5.1.98 |
Target Class | Enzymes |
Gene Biotype | PROTEIN_CODING |
GuideToPharmacology Gene Category Name | 3.5.1.- Histone deacetylases (HDACs) |
GuideToPharmacology Gene Category ID | 848 |
DNA REPAIR |
DRUGGABLE GENOME |
ENZYME |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Trial Name | PXD101 |
Novel drug target | Established target |
Direct Interaction | yes |
n/a |
Trial Name | MGCD-0103 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Trial Name | CUDC-101 |
Novel drug target | Established target |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
n/a |
Trial Name | Chidamide, HBI-8000 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Notes | |
Trial Name | PCI-27483, CRA-024781 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Notes | |
Trial Name | ITF2357,Givinostat |
Novel drug target | Established target |
inhibitor (inhibitory) |
Direct Interaction? | True |
Endogenous Drug? | False |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Trial Name | Panobinostat |
Novel drug target | Established target |
Notes |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
Trial Name | Depsipeptide |
n/a |
Novel drug target | Established target |
Trial Name | Resminostat |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
n/a |
Trial Name | AR-42 |
Novel drug target | Established target |
HDAC10 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
HDAC10 | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
18128 | HUGO Gene ID |
18128 | HUGO Gene Symbol |
histone deacetylase 10 | HUGO Gene Name |
GuideToPharmacology Gene Category Name | 3.5.1.- Histone deacetylases (HDACs) |
GuideToPharmacology Gene Category ID | 848 |
ENZYME |
HDAC10 | DrugBank Gene Name |
Q969S8 | UniProt Accession |
83933 | Entrez Gene Id |
HDAC10 | Gene Symbol |
ENSG00000100429 | Gene Symbol |
HDAC10 | Ensembl Id |
DRUGGABLE GENOME |
HDAC10 | GENE_SYMBOL |
Histone deacetylase 10 | UNIPROT |
HD10 | UNIPROT |
HDAC10 | TTD Gene Abbreviation |
T94324 | TTD Target ID |
DNA REPAIR |