10014 |
HISTONE DEACETYLASE 5 |
HDAC5 |
HD5 |
NY-CO-9 |
605315 |
14068 |
ENSG00000108840 |
OTTHUMG00000181806 |
KIAA0600 |
Antigen NY-CO-9 |
2660 |
Q9UQL6 |
T07930 |
NM_005474 |
NP_005465 |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
Gene Biotype | PROTEIN_CODING |
GuideToPharmacology Gene Category Name | 3.5.1.- Histone deacetylases (HDACs) |
GuideToPharmacology Gene Category ID | 848 |
DRUG RESISTANCE |
TRANSCRIPTION FACTOR BINDING |
DRUGGABLE GENOME |
ENZYME |
TRANSCRIPTION FACTOR |
inhibitor (inhibitory) |
Direct Interaction? | False |
Endogenous Drug? | False |
Specific Action of the Ligand | Inhibition |
n/a |
Trial Name | MGCD-0103 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Trial Name | CUDC-101 |
Novel drug target | Established target |
Notes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase inhibitor |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Notes | |
Trial Name | ITF2357,Givinostat |
Novel drug target | Established target |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase inhibitor |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Trial Name | SB939 |
Novel drug target | Established target |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Direct Interaction? | False |
Endogenous Drug? | False |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Notes | |
Trial Name | Panobinostat |
Novel drug target | Established target |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Notes |
inhibitor (inhibitory) |
Direct Interaction? | False |
Endogenous Drug? | False |
Specific Action of the Ligand | Inhibition |
n/a |
Trial Name | Resminostat |
Novel drug target | Established target |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
n/a |
Trial Name | AR-42 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
HDAC5 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
HDAC5 | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
14068 | HUGO Gene ID |
14068 | HUGO Gene Symbol |
histone deacetylase 5 | HUGO Gene Name |
GuideToPharmacology Gene Category Name | 3.5.1.- Histone deacetylases (HDACs) |
GuideToPharmacology Gene Category ID | 848 |
ENZYME |
HDAC5 | Gene Symbol |
KIAA0600 | GENE_SYMBOL |
HDAC5 | GENE_SYMBOL |
Histone deacetylase 5 | UNIPROT |
ENSG00000108840 | Gene Symbol |
HDAC5 | Ensembl Id |
DRUGGABLE GENOME |
Histone deacetylase 5 | Gene Name |
Q9UQL6 | UniProt ID |
TRANSCRIPTION FACTOR |
KIAA0600 | GO Gene Synonym |
DRUG RESISTANCE, TRANSCRIPTION FACTOR BINDING |
HDAC5 | TTD Gene Abbreviation |
T07930 | TTD Target ID |