DGIdb - HDAC5 Gene Record

HDAC5 10014 Druggable GenomeDrug Resistance

Alternate Names:

10014
HISTONE DEACETYLASE 5
HDAC5
HD5
NY-CO-9
605315
14068
ENSG00000108840
OTTHUMG00000181806
KIAA0600
Antigen NY-CO-9
2660
Q9UQL6
T07930
NM_005474
NP_005465

Gene Info:

Target Class	Enzymes
Target Subclass	EC:3.5.1.98
Gene Biotype	PROTEIN_CODING
GuideToPharmacology Gene Category Name	3.5.1.- Histone deacetylases (HDACs)
GuideToPharmacology Gene Category ID	848

(6 More Sources)

Gene Categories: Category Details

DRUG RESISTANCE
TRANSCRIPTION FACTOR BINDING
DRUGGABLE GENOME
ENZYME
TRANSCRIPTION FACTOR

Publications:

Hutt DM et al., 2010, Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis., Nat Chem Biol
Souto JA et al., 2010, Synthesis and biological characterization of the histone deacetylase inhibitor largazole and C7- modified analogues., J Med Chem
Campbell CT et al., 2008, Targeting pro-invasive oncogenes with short chain fatty acid-hexosamine analogues inhibits the mobility of metastatic MDA-MB-231 breast cancer cells., J Med Chem
Marson CM et al., 2013, Discovery of potent, isoform-selective inhibitors of histone deacetylase containing chiral heterocyclic capping groups and a N-(2-aminophenyl)benzamide binding unit., J Med Chem
Marson CM et al., 2015, Potent and Selective Inhibitors of Histone Deacetylase-3 Containing Chiral Oxazoline Capping Groups and a N-(2-Aminophenyl)-benzamide Binding Unit., J Med Chem
Kozlov MV et al., 2015, Pyridine hydroxamic acids are specific anti-HCV agents affecting HDAC6., Bioorg Med Chem Lett
Perrino E et al., 2008, New sulfurated derivatives of valproic acid with enhanced histone deacetylase inhibitory activity., Bioorg Med Chem Lett
Herman D et al., 2006, Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia., Nat Chem Biol
Petrelli R et al., 2014, From the covalent linkage of drugs to novel inhibitors of ribonucleotide reductase: synthesis and biological evaluation of valproic esters of 3'-C-methyladenosine., Bioorg Med Chem Lett
Mimori S et al., 2013, 4-Phenylbutyric acid protects against neuronal cell death by primarily acting as a chemical chaperone rather than histone deacetylase inhibitor., Bioorg Med Chem Lett
Chen IH et al., 2009, Cytotoxic triterpenoids from the stems of Microtropis japonica., J Nat Prod
Benelkebir H et al., 2011, Total synthesis of largazole and analogues: HDAC inhibition, antiproliferative activity and metabolic stability., Bioorg Med Chem
Bhansali P et al., 2014, Synthesis and biological evaluation of largazole analogues with modified surface recognition cap groups., Eur J Med Chem
Shi Y et al., 2007, Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition., Bioorg Med Chem Lett
Grolla AA et al., 2009, Synthesis, biological evaluation, and molecular docking of Ugi products containing a zinc-chelating moiety as novel inhibitors of histone deacetylases., J Med Chem
Yang W et al., 2015, Design, synthesis and biological evaluation of isoquinoline-based derivatives as novel histone deacetylase inhibitors., Bioorg Med Chem
Guerrant W et al., 2013, Dual-acting histone deacetylase-topoisomerase I inhibitors., Bioorg Med Chem Lett
Guerrant W et al., 2012, Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors., J Med Chem
Neelarapu R et al., 2011, Design, synthesis, docking, and biological evaluation of novel diazide-containing isoxazole- and pyrazole-based histone deacetylase probes., J Med Chem
Dallavalle S et al., 2009, Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors., Eur J Med Chem
Olsen CA et al., 2009, Discovery of potent and selective histone deacetylase inhibitors via focused combinatorial libraries of cyclic alpha3beta-tetrapeptides., J Med Chem
Thomas M et al., 2008, Synthesis and biological evaluation of glucuronide prodrugs of the histone deacetylase inhibitor CI-994 for application in selective cancer chemotherapy., Bioorg Med Chem
Marrazzo A et al., 2011, Antiproliferative activity of phenylbutyrate ester of haloperidol metabolite II [(±)-MRJF4] in prostate cancer cells., Eur J Med Chem
Charrier C et al., 2009, Synthesis and modeling of new benzofuranone histone deacetylase inhibitors that stimulate tumor suppressor gene expression., J Med Chem
Fass et al., 2010, Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin., ACS Med Chem Lett
Hong S et al., 2015, Efficient synthesis and biological activity of Psammaplin A and its analogues as antitumor agents., Eur J Med Chem

BELINOSTAT HDAC5

Interaction Score: 0.64

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Inhibition

PMIDs:
25937017

Sources:
DTC TdgClinicalTrial TALC GuideToPharmacology ChemblInteractions
MOCETINOSTAT HDAC5

Interaction Score: 0.46

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name MGCD-0103

Novel drug target Established target

PMIDs:
23829483 26287310

Sources:
DTC TdgClinicalTrial
CUDC-101 HDAC5

Interaction Score: 0.43

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name CUDC-101

Novel drug target Established target

Notes

PMIDs:
None found

Sources:
TdgClinicalTrial TALC GuideToPharmacology ChemblInteractions
TACEDINALINE HDAC5

Interaction Score: 0.41

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Histone deacetylase inhibitor

PMIDs:
18692397

Sources:
DTC ChemblInteractions
TRICHOSTATIN HDAC5

Interaction Score: 0.39

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21055848 16921367 19966789 19385600

Sources:
DTC
SCRIPTAID HDAC5

Interaction Score: 0.37

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Direct Interaction? False

PMIDs:
19966789

Sources:
DTC GuideToPharmacology
GIVINOSTAT HDAC5

Interaction Score: 0.37

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Notes

Trial Name ITF2357,Givinostat

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial TALC GuideToPharmacology
VORINOSTAT HDAC5

Interaction Score: 0.35

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Notes

Specific Action of the Ligand Inhibition

Endogenous Drug? False

PMIDs:
19344175 19966789 26211462 23622981 22260166 20491440 21548582 19084294

Sources:
DTC TALC GuideToPharmacology
VALPROIC ACID HDAC5

Interaction Score: 0.33

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18294844 16921367 25304896

Sources:
DTC
ENTINOSTAT HDAC5

Interaction Score: 0.33

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Histone deacetylase inhibitor

PMIDs:
19966789 20491440

Sources:
DTC ChemblInteractions
SUBEROHYDROXAMIC ACID HDAC5

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16921367

Sources:
DTC
PHENYLBUTYRYLHYDROXAMIC ACID HDAC5

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21874153

Sources:
DTC
BUTYRYLHYDROXAMIC ACID HDAC5

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21874153

Sources:
DTC
CHEMBL1650245 HDAC5

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24044874

Sources:
DTC
CHEMBL324053 HDAC5

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16921367

Sources:
DTC
APICIDIN HDAC5

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19705846

Sources:
DTC
CHEMBL117487 HDAC5

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17566732

Sources:
DTC
URSOLIC ACID HDAC5

Interaction Score: 0.25

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19534471

Sources:
DTC
NANATINOSTAT HDAC5

Interaction Score: 0.25

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology
PRACINOSTAT HDAC5

Interaction Score: 0.25

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name SB939

Novel drug target Established target

Specific Action of the Ligand Inhibition

PMIDs:
None found

Sources:
TdgClinicalTrial GuideToPharmacology
BUTANOIC ACID HDAC5

Interaction Score: 0.25

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19053749

Sources:
DTC
PSAMMAPLIN A HDAC5

Interaction Score: 0.23

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
25884112

Sources:
DTC
ROMIDEPSIN HDAC5

Interaction Score: 0.22

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Inhibition

PMIDs:
None found

Sources:
TdgClinicalTrial GuideToPharmacology ChemblInteractions
PHENYLBUTANOIC ACID HDAC5

Interaction Score: 0.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24044874

Sources:
DTC
LARGAZOLE HDAC5

Interaction Score: 0.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21420302 25203782 20491440

Sources:
DTC
DEPAKOTE HDAC5

Interaction Score: 0.19

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Notes

PMIDs:
None found

Sources:
TALC
PANOBINOSTAT HDAC5

Interaction Score: 0.18

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Notes

Trial Name Panobinostat

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial TALC
AN-9 HDAC5

Interaction Score: 0.17

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Notes

PMIDs:
None found

Sources:
TALC
PANOBINOSTAT LACTATE HDAC5

Interaction Score: 0.15

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Histone deacetylase inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
ABEXINOSTAT HDAC5

Interaction Score: 0.14

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Notes

PMIDs:
None found

Sources:
TALC
DACINOSTAT HDAC5

Interaction Score: 0.14

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Inhibition

PMIDs:
None found

Sources:
GuideToPharmacology
RESMINOSTAT HDAC5

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name Resminostat

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial
QUISINOSTAT HDAC5

Interaction Score: 0.12

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology
AR-42 HDAC5

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name AR-42

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial
7-ETHYL-10-HYDROXYCAMPTOTHECIN HDAC5

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23622981

Sources:
DTC
HINOKITIOL HDAC5

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FIMEPINOSTAT HDAC5

Interaction Score: 0.08

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Histone deacetylase inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
DAUNORUBICIN HDAC5

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22260166

Sources:
DTC

Ensembl: ENSG00000108840
- Version: 101_38
Alternate Names:

HDAC5 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
TdgClinicalTrial: Q9UQL6
- Version: January-2014
Alternate Names:

HDAC5 Gene Symbol

Gene Info:

Target Class Enzymes

Target Subclass EC:3.5.1.98

Publications:
GuideToPharmacology: 10014
- Version: 29-September-2020
Alternate Names:

14068 HUGO Gene ID

14068 HUGO Gene Symbol

histone deacetylase 5 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name 3.5.1.- Histone deacetylases (HDACs)

GuideToPharmacology Gene Category ID 848

Gene Categories:

ENZYME

Publications:

DTC: HDAC5

Version: 02-September-2020

Alternate Names:

Gene Info:

Publications:

Mimori S et al., 2013, 4-Phenylbutyric acid protects against neuronal cell death by primarily acting as a chemical chaperone rather than histone deacetylase inhibitor., Bioorg Med Chem Lett

Thomas M et al., 2008, Synthesis and biological evaluation of glucuronide prodrugs of the histone deacetylase inhibitor CI-994 for application in selective cancer chemotherapy., Bioorg Med Chem

Grolla AA et al., 2009, Synthesis, biological evaluation, and molecular docking of Ugi products containing a zinc-chelating moiety as novel inhibitors of histone deacetylases., J Med Chem

TALC: HDAC5
- Version: 12-May-2016
Alternate Names:

HDAC5 Gene Symbol

Gene Info:

Publications:
ChemblInteractions: KIAA0600
- Version: chembl_23
Alternate Names:

KIAA0600 GENE_SYMBOL

HDAC5 GENE_SYMBOL

Histone deacetylase 5 UNIPROT

Gene Info:

Publications:
HingoraniCasas: ENSG00000108840
- Version: 31-May-2017
Alternate Names:

ENSG00000108840 Gene Symbol

HDAC5 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
Pharos: HDAC5
- Version: 03-September-2020
Alternate Names:

Histone deacetylase 5 Gene Name

Q9UQL6 UniProt ID

Gene Info:

Gene Categories:

TRANSCRIPTION FACTOR

Publications:
GO: HDAC5
- Version: 05-September-2020
Alternate Names:

KIAA0600 GO Gene Synonym

Gene Info:

Gene Categories:

DRUG RESISTANCE, TRANSCRIPTION FACTOR BINDING

Publications:
TTD: Histone deacetylase 5
- Version: 2020.06.01
Alternate Names:

HDAC5 TTD Gene Abbreviation

T07930 TTD Target ID

Gene Info:

Publications:

Direct Interaction?	False
Endogenous Drug?	False
Specific Action of the Ligand	Inhibition

Direct Interaction	yes
Mechanism of Interaction	Histone deacetylase inhibitor

Notes
Trial Name	ITF2357,Givinostat
Novel drug target	Established target

Trial Name	SB939
Novel drug target	Established target
Specific Action of the Ligand	Inhibition

Notes
Trial Name	Panobinostat
Novel drug target	Established target

14068	HUGO Gene ID
14068	HUGO Gene Symbol
histone deacetylase 5	HUGO Gene Name

KIAA0600	GENE_SYMBOL
HDAC5	GENE_SYMBOL
Histone deacetylase 5	UNIPROT

HDAC5 Gene Record

HDAC5 10014 Druggable GenomeDrug Resistance

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction? False Endogenous Drug? False Specific Action of the Ligand Inhibition

PMIDs: 25937017

Sources: DTC TdgClinicalTrial TALC GuideToPharmacology ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info: Trial Name MGCD-0103 Novel drug target Established target

PMIDs: 23829483 26287310

Sources: DTC TdgClinicalTrial

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Trial Name CUDC-101 Novel drug target Established target Notes

PMIDs: None found

Sources: TdgClinicalTrial TALC GuideToPharmacology ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Histone deacetylase inhibitor

PMIDs: 18692397

Sources: DTC ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21055848 16921367 19966789 19385600

Sources: DTC

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False

PMIDs: 19966789

Sources: DTC GuideToPharmacology

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Notes Trial Name ITF2357,Givinostat Novel drug target Established target

PMIDs: None found

Sources: TdgClinicalTrial TALC GuideToPharmacology

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Notes Specific Action of the Ligand Inhibition Endogenous Drug? False

PMIDs: 19344175 19966789 26211462 23622981 22260166 20491440 21548582 19084294

Sources: DTC TALC GuideToPharmacology

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 18294844 16921367 25304896

Sources: DTC

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Histone deacetylase inhibitor

PMIDs: 19966789 20491440

Sources: DTC ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16921367

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21874153

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21874153

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24044874

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16921367

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19705846

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17566732

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19534471

Sources: DTC

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Inhibition

PMIDs:
25937017

Sources:
DTC TdgClinicalTrial TALC GuideToPharmacology ChemblInteractions

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name MGCD-0103

Novel drug target Established target

PMIDs:
23829483 26287310

Sources:
DTC TdgClinicalTrial

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name CUDC-101

Novel drug target Established target

Notes

PMIDs:
None found

Sources:
TdgClinicalTrial TALC GuideToPharmacology ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Histone deacetylase inhibitor

PMIDs:
18692397

Sources:
DTC ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
21055848 16921367 19966789 19385600

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Direct Interaction? False

PMIDs:
19966789

Sources:
DTC GuideToPharmacology

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Notes

Trial Name ITF2357,Givinostat

Novel drug target Established target

PMIDs:
None found

Sources:
TdgClinicalTrial TALC GuideToPharmacology

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Notes

Specific Action of the Ligand Inhibition

Endogenous Drug? False

PMIDs:
19344175 19966789 26211462 23622981 22260166 20491440 21548582 19084294

Sources:
DTC TALC GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
18294844 16921367 25304896

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Histone deacetylase inhibitor

PMIDs:
19966789 20491440

Sources:
DTC ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
16921367

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21874153

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21874153

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
24044874

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
16921367

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
19705846

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
17566732

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
19534471

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name SB939

Novel drug target Established target

Specific Action of the Ligand Inhibition

PMIDs:
None found

Sources:
TdgClinicalTrial GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
19053749

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
25884112

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Inhibition

PMIDs:
None found

Sources:
TdgClinicalTrial GuideToPharmacology ChemblInteractions