10013 |
HISTONE DEACETYLASE 6 |
HDAC6 |
CPBHM |
HD6 |
JM21 |
PPP1R90 |
300272 |
14064 |
ENSG00000094631 |
OTTHUMG00000034496 |
BE0002368 |
Q9UBN7 |
KIAA0901 |
HDAC6_HUMAN |
2618 |
T22274 |
NM_006044 |
NP_006035 |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
Target Main Class | Enzymes |
Target Subclass | 3.5.1.98 |
Gene Biotype | PROTEIN_CODING |
GuideToPharmacology Gene Category Name | 3.5.1.- Histone deacetylases (HDACs) |
GuideToPharmacology Gene Category ID | 848 |
DRUGGABLE GENOME |
ENZYME |
TRANSCRIPTION FACTOR |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Trial Name | ACY-1215 |
Novel drug target | Established target |
Direct Interaction? | False |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Trial Name | Merck |
Novel drug target | Established target |
Mechanism of Interaction | Histone deacetylase 6 inhibitor |
inhibitor (inhibitory) |
Notes | |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | True |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | Depsipeptide |
Mechanism of Interaction | Histone deacetylase inhibitor |
n/a |
Trial Name | MGCD-0103 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Notes | |
Trial Name | Panobinostat |
Novel drug target | Established target |
inhibitor (inhibitory) |
Direct Interaction? | False |
Endogenous Drug? | False |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Notes | |
Direct Interaction? | False |
Endogenous Drug? | False |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Notes | |
Trial Name | PCI-27483, CRA-024781 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
n/a |
Trial Name | SB939 |
Novel drug target | Established target |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase inhibitor |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
n/a |
Trial Name | AR-42 |
Novel drug target | Established target |
HDAC6 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
HDAC6_HUMAN | Uniprot Id |
Q9UBN7 | Uniprot Accession |
ENSG00000094631 | Ensembl Gene Id |
Target Main Class | Enzymes |
Target Subclass | 3.5.1.98 |
HDAC6 | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
14064 | HUGO Gene ID |
14064 | HUGO Gene Symbol |
histone deacetylase 6 | HUGO Gene Name |
GuideToPharmacology Gene Category Name | 3.5.1.- Histone deacetylases (HDACs) |
GuideToPharmacology Gene Category ID | 848 |
ENZYME |
HDAC6 | DrugBank Gene Name |
Q9UBN7 | UniProt Accession |
10013 | Entrez Gene Id |
HDAC6 | TTD Gene Abbreviation |
T22274 | TTD Target ID |
KIAA0901 | GENE_SYMBOL |
HDAC6 | GENE_SYMBOL |
Histone deacetylase 6 | UNIPROT |
ENSG00000094631 | Gene Symbol |
HDAC6 | Ensembl Id |
DRUGGABLE GENOME |
HDAC6 | Gene Symbol |
Histone deacetylase 6 | Gene Name |
Q9UBN7 | UniProt ID |
TRANSCRIPTION FACTOR |