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HSPA8 Gene Record

  • Summary
  • Interactions
  • Claims
  • HSPA8 3312

    Alternate Names:

    3312
    HEAT SHOCK PROTEIN FAMILY A (HSP70) MEMBER 8
    HSPA8
    HEL-33
    HEL-S-72p
    HSC54
    HSC70
    HSC71
    HSP71
    HSP73
    HSPA10
    LAP-1
    LAP1
    NIP71
    600816
    5241
    ENSG00000109971
    OTTHUMG00000166030
    LPS-associated protein 1
    Lipopolysaccharide-associated protein 1
    Heat shock 70 kDa protein 8
    Heat shock cognate 71 kDa protein

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    TUMOR SUPPRESSOR

    Publications:

    Castagna et al., 2004, A proteomic approach to cisplatin resistance in the cervix squamous cell carcinoma cell line A431., Proteomics
    Sumioka et al., 2004, Potential roles of hepatic heat shock protein 25 and 70i in protection of mice against acetaminophen-induced liver injury., Life Sci.
    Miyazaki et al., 2004, 73-kDa molecular chaperone HSP73 is a direct target of antibiotic gentamicin., J. Biol. Chem.
    Li et al., 1995, Effects of dexamethasone, heat shock, and serum responses on the inhibition of Hsc70 synthesis by antisense RNA in NIH 3T3 cells., J. Cell. Physiol.
    Lee et al., 1995, Induction of 73-kDa and 90-kDa heat shock protein expression in HL60 cells during differentiation., Tohoku J. Exp. Med.
    Duguez et al., 2003, Myogenic and nonmyogenic cells differentially express proteinases, Hsc/Hsp70, and BAG-1 during skeletal muscle regeneration., Am. J. Physiol. Endocrinol. Metab.
  • ADENOSINE DIPHOSPHATE   HSPA8

    Interaction Score: 4.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL487046   HSPA8

    Interaction Score: 4.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ADENOSINE TRIPHOSPHATE   HSPA8

    Interaction Score: 2.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL471004   HSPA8

    Interaction Score: 2.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL502775   HSPA8

    Interaction Score: 2.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • BUPIVACAINE   HSPA8

    Interaction Score: 0.88

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12791605


    Sources:
    NCI

  • ANTIBIOTIC   HSPA8

    Interaction Score: 0.88

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14966137


    Sources:
    NCI

  • CHEMBL1481974   HSPA8

    Interaction Score: 0.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TRETINOIN   HSPA8

    Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8578578


    Sources:
    NCI

  • ACETAMINOPHEN   HSPA8

    Interaction Score: 0.23

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15010265


    Sources:
    NCI

  • ELLAGIC ACID   HSPA8

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   HSPA8

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DEXAMETHASONE   HSPA8

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    7542664


    Sources:
    NCI

  • CISPLATIN   HSPA8

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15378690


    Sources:
    NCI

  • Ensembl: ENSG00000109971

    • Version: 101_38

    Alternate Names:
    HSPA8 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: HSPA8

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Castagna et al., 2004, A proteomic approach to cisplatin resistance in the cervix squamous cell carcinoma cell line A431., Proteomics
    Duguez et al., 2003, Myogenic and nonmyogenic cells differentially express proteinases, Hsc/Hsp70, and BAG-1 during skeletal muscle regeneration., Am. J. Physiol. Endocrinol. Metab.
    Lee et al., 1995, Induction of 73-kDa and 90-kDa heat shock protein expression in HL60 cells during differentiation., Tohoku J. Exp. Med.

  • ChemblInteractions: HSC70

    • Version: chembl_23

    Alternate Names:
    HSP73 GENE_SYMBOL
    HSPA10 GENE_SYMBOL
    HSPA8 GENE_SYMBOL

    Gene Info:

    Publications:

  • GO: HSPA8

    • Version: 01-February-2022

    Alternate Names:
    HSC70 GO Gene Synonym
    HSP73 GO Gene Synonym
    HSPA10 GO Gene Synonym

    Gene Info:

    Gene Categories:
    TUMOR SUPPRESSOR

    Publications:

  • DTC: HSPA8

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21