DGIdb - HSPA8 Gene Record

HSPA8 3312

Alternate Names:

3312
HEAT SHOCK PROTEIN FAMILY A (HSP70) MEMBER 8
HSPA8
HEL-33
HEL-S-72p
HSC54
HSC70
HSC71
HSP71
HSP73
HSPA10
LAP-1
LAP1
NIP71
600816
5241
ENSG00000109971
OTTHUMG00000166030
LPS-associated protein 1
Lipopolysaccharide-associated protein 1
Heat shock 70 kDa protein 8
Heat shock cognate 71 kDa protein

Gene Info:

Gene Biotype	PROTEIN_CODING

(1 More Sources)

Gene Categories: Category Details

TUMOR SUPPRESSOR

Publications:

Castagna et al., 2004, A proteomic approach to cisplatin resistance in the cervix squamous cell carcinoma cell line A431., Proteomics
Sumioka et al., 2004, Potential roles of hepatic heat shock protein 25 and 70i in protection of mice against acetaminophen-induced liver injury., Life Sci.
Miyazaki et al., 2004, 73-kDa molecular chaperone HSP73 is a direct target of antibiotic gentamicin., J. Biol. Chem.
Li et al., 1995, Effects of dexamethasone, heat shock, and serum responses on the inhibition of Hsc70 synthesis by antisense RNA in NIH 3T3 cells., J. Cell. Physiol.
Lee et al., 1995, Induction of 73-kDa and 90-kDa heat shock protein expression in HL60 cells during differentiation., Tohoku J. Exp. Med.
Duguez et al., 2003, Myogenic and nonmyogenic cells differentially express proteinases, Hsc/Hsp70, and BAG-1 during skeletal muscle regeneration., Am. J. Physiol. Endocrinol. Metab.

ADENOSINE DIPHOSPHATE HSPA8

Interaction Score: 4.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL487046 HSPA8

Interaction Score: 4.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ADENOSINE TRIPHOSPHATE HSPA8

Interaction Score: 2.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL471004 HSPA8

Interaction Score: 2.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL502775 HSPA8

Interaction Score: 2.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BUPIVACAINE HSPA8

Interaction Score: 0.88

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12791605

Sources:
NCI
ANTIBIOTIC HSPA8

Interaction Score: 0.88

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14966137

Sources:
NCI
CHEMBL1481974 HSPA8

Interaction Score: 0.55

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TRETINOIN HSPA8

Interaction Score: 0.3

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8578578

Sources:
NCI
ACETAMINOPHEN HSPA8

Interaction Score: 0.23

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15010265

Sources:
NCI
ELLAGIC ACID HSPA8

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE HSPA8

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DEXAMETHASONE HSPA8

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7542664

Sources:
NCI
CISPLATIN HSPA8

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15378690

Sources:
NCI

Ensembl: ENSG00000109971
- Version: 101_38
Alternate Names:

HSPA8 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

NCI: HSPA8

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Castagna et al., 2004, A proteomic approach to cisplatin resistance in the cervix squamous cell carcinoma cell line A431., Proteomics

Duguez et al., 2003, Myogenic and nonmyogenic cells differentially express proteinases, Hsc/Hsp70, and BAG-1 during skeletal muscle regeneration., Am. J. Physiol. Endocrinol. Metab.

Lee et al., 1995, Induction of 73-kDa and 90-kDa heat shock protein expression in HL60 cells during differentiation., Tohoku J. Exp. Med.

ChemblInteractions: HSC70
- Version: chembl_23
Alternate Names:

HSP73 GENE_SYMBOL

HSPA10 GENE_SYMBOL

HSPA8 GENE_SYMBOL

Gene Info:

Publications:
GO: HSPA8
- Version: 01-February-2022
Alternate Names:

HSC70 GO Gene Synonym

HSP73 GO Gene Synonym

HSPA10 GO Gene Synonym

Gene Info:

Gene Categories:

TUMOR SUPPRESSOR

Publications:
DTC: HSPA8
- Version: 02-September-2020
Alternate Names:

Gene Info:

Publications:

HSC70	GO Gene Synonym
HSP73	GO Gene Synonym
HSPA10	GO Gene Synonym

HSP73	GENE_SYMBOL
HSPA10	GENE_SYMBOL
HSPA8	GENE_SYMBOL

HSPA8 Gene Record

HSPA8 3312

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12791605

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 14966137

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8578578

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15010265

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7542664

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15378690

Sources: NCI

Ensembl: ENSG00000109971

Alternate Names: HSPA8 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

NCI: HSPA8

Alternate Names:

Gene Info:

ChemblInteractions: HSC70

Alternate Names: HSP73 GENE_SYMBOL HSPA10 GENE_SYMBOL HSPA8 GENE_SYMBOL

Gene Info:

Publications:

GO: HSPA8

Alternate Names: HSC70 GO Gene Synonym HSP73 GO Gene Synonym HSPA10 GO Gene Synonym

Gene Info:

Gene Categories: TUMOR SUPPRESSOR

Publications:

DTC: HSPA8

Alternate Names:

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
12791605

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
14966137

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
8578578

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15010265

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
7542664

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15378690

Sources:
NCI

Alternate Names:

HSPA8 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

HSP73 GENE_SYMBOL

HSPA10 GENE_SYMBOL

HSPA8 GENE_SYMBOL

Alternate Names:

HSC70 GO Gene Synonym

HSP73 GO Gene Synonym

HSPA10 GO Gene Synonym

Gene Categories:

TUMOR SUPPRESSOR