• HTR3C 170572 Druggable Genome

    Alternate Names:

    170572
    5-HYDROXYTRYPTAMINE RECEPTOR 3C
    HTR3C
    610121
    24003
    ENSG00000178084
    OTTHUMG00000156862
    Q8WXA8
    5HT3C_HUMAN
    5-HT3C
    5-HT3-C
    Serotonin receptor 3C
    375
    NP_570126
    NM_130770
    5-HYDROXYTRYPTAMINE RECEPTOR 3 SUBUNIT C [SOURCE:REFSEQ_PEPTIDE;ACC:NP_570126]

    Gene Info:

    Interpro Short Name Neur_chan_lig-bd
    Interpro Acc IPR006202
    Interpro Short Name Neur_channel
    Interpro Type Domain
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Neurotransmitter-gated ion-channel
    Interpro Type Family
    Interpro Acc IPR006201
    Uniprot Status Swiss-Prot
    Human Readable Name ION CHANNEL
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Neurotransmitter-gated ion-channel ligand-binding
    GuideToPharmacology Gene Category Name 5-HT<sub>3</sub> receptors
    GuideToPharmacology Gene Category ID 68
    Target Class Receptors
    Target Subclass TC:1.A.9
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    ION CHANNEL
    DRUGGABLE GENOME

    Publications:

  • Interaction Score: 2.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name Pumosetrag
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 2.13

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Serotonin 3 (5-HT3) receptor antagonist

    PMIDs:
    None found


  • Interaction Score: 1.59

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name dolasetron mesylate,Anzemet
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 0.98

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name granisetron nasal spray
    Novel drug target Established target
    Trial Name granisetron (intranasal), TRG

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 0.98

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Serotonin 3 (5-HT3) receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    HTR3C Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000178084 Ensembl Gene Id
    5-HYDROXYTRYPTAMINE RECEPTOR 3 SUBUNIT C [SOURCE:REFSEQ_PEPTIDE;ACC:NP_570126] Description
    HTR3C Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    HTR3C Uniprot Gene Name
    5HT3C_HUMAN Uniprot Id
    Q8WXA8 Uniprot Accession

    Gene Info:
    Interpro Short Name Neur_chan_lig-bd
    Interpro Acc IPR006202
    Interpro Short Name Neur_channel

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: January-2014

    Alternate Names:
    HTR3C Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass TC:1.A.9

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    24003 HUGO Gene ID
    24003 HUGO Gene Symbol
    5-hydroxytryptamine receptor 3C HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name 5-HT<sub>3</sub> receptors
    GuideToPharmacology Gene Category ID 68

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: chembl_23

    Alternate Names:
    HTR3C GENE_SYMBOL
    5-hydroxytryptamine receptor 3C UNIPROT
    Serotonin receptor 3C UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000178084 Gene Symbol
    HTR3C Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    5-hydroxytryptamine receptor 3C Gene Name
    Q8WXA8 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: