• HTR5A 3361 Druggable Genome

    Alternate Names:

    3361
    5-HYDROXYTRYPTAMINE RECEPTOR 5A
    HTR5A
    5-HT5A
    601305
    5300
    ENSG00000157219
    OTTHUMG00000151327
    P47898
    5HT5A_HUMAN
    5-HYDROXYTRYPTAMINE 5A RECEPTOR (5-HT-5A) (SEROTONIN RECEPTOR 5A) (5- HT-5). [SOURCE:UNIPROT/SWISSPROT;ACC:P47898]
    10
    5-HT<sub>5A</sub> receptor
    5-HT 5A receptor
    T15571
    NM_024012
    NP_076917

    Gene Info:

    Interpro Short Name 7TM_GPCR_Rhodpsn
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Type Family
    Interpro Name GPCR, rhodopsin-like, 7TM
    Interpro Acc IPR000276
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin
    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name 5-Hydroxytryptamine receptors
    GuideToPharmacology Gene Category ID 1
    (4 More Sources)

    Gene Categories: Category Details

    G PROTEIN COUPLED RECEPTOR
    DRUGGABLE GENOME
  • Interaction Score: 0.68

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Trial Name Asenapine
    Novel drug target Established target

  • Interaction Score: 0.51

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.51

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Endogenous Drug? False
    Specific Action of the Ligand Full agonist

    PMIDs:
    None found


  • Interaction Score: 0.51

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Endogenous Drug? False
    Specific Action of the Ligand Antagonist

    PMIDs:
    None found


  • Interaction Score: 0.41

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.33

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.27

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.25

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.25

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.24

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True

    PMIDs:
    None found


  • Interaction Score: 0.23

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.22

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.22

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.06

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    HTR5A Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    HTR5A Uniprot Gene Name
    ENSG00000157219 Ensembl Gene Id
    P47898 Uniprot Accession

    Gene Info:
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME

    Publications:

    • Version: January-2014

    Alternate Names:
    HTR5A Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    HTR5A Display Id
    5-HYDROXYTRYPTAMINE 5A RECEPTOR (5-HT-5A) (SEROTONIN RECEPTOR 5A) (5- HT-5). [SOURCE:UNIPROT/SWISSPROT;ACC:P47898] Description
    ENSG00000157219 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    5300 HUGO Gene ID
    5300 HUGO Gene Symbol
    5-hydroxytryptamine receptor 5A HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name 5-Hydroxytryptamine receptors
    GuideToPharmacology Gene Category ID 1

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000157219 Gene Symbol
    HTR5A Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    3361 Gene ID
    5-HT5A dGene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    HTR5A TTD Gene Abbreviation
    T15571 TTD Target ID

    Gene Info:

    Publications: