• IDE 3416 Druggable Genome

    Alternate Names:

    3416
    INSULIN DEGRADING ENZYME
    IDE
    INSULYSIN
    146680
    5381
    ENSG00000119912
    OTTHUMG00000018759
    P14735
    IDE_HUMAN
    insulin-degrading enzyme
    BE0001183
    2371
    NP_001159418|NP_004960
    NM_001165946|NM_004969
    INSULIN-DEGRADING ENZYME (EC 3.4.24.56) (INSULYSIN) (INSULINASE) (INSULIN PROTEASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P14735]
    T81900

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Name Peptidase M16, zinc-binding site
    Uniprot Status Swiss-Prot
    Human Readable Name NEUTRAL ZINC METALLOPEPTIDASE
    Interpro Short Name Pept_M16_Zn_BS
    Interpro Type Binding_site
    Interpro Acc IPR001431
    Uniprot Evidence 1: Evidence at protein level
    GuideToPharmacology Gene Category Name M16: Pitrilysin
    GuideToPharmacology Gene Category ID 744
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    CELL SURFACE
    NEUTRAL ZINC METALLOPEPTIDASE
    PROTEASE
    EXTERNAL SIDE OF PLASMA MEMBRANE
    DRUGGABLE GENOME
    ENZYME
  • Interaction Score: 11.36

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    11752352 8484964


    Sources:
    DrugBank TTD

  • Interaction Score: 1.89

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 1.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.63

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.57

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC