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IFNA1 Gene Record

  • Summary
  • Interactions
  • Claims
  • IFNA1 3439 Druggable Genome

    Alternate Names:

    3439
    INTERFERON ALPHA 1
    IFNA1
    IFL
    IFN
    IFN-ALPHA
    IFN-alphaD
    IFNA13
    IFNA@
    147660
    5417
    ENSG00000197919
    OTTHUMG00000019673
    INTERFERON ALPHA
    IFNA
    T45598
    Interferon
    T73671
    P01562
    Interferon alpha-1/13

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    KINASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

    Won et al., 1993, Alpha-methyl-p-tyrosine reduces poly I:C-induced augmenting interferon production and splenic natural killer cell activity in mice., Pharmacology
    Calvert et al., 1990, Effects of the copper chelators diethyldithiocarbamate and bathocuproine sulfonate on interferon and its antiviral state., J. Interferon Res.
    Megyeri et al., 1995, Stimulation of interferon and cytokine gene expression by imiquimod and stimulation by Sendai virus utilize similar signal transduction pathways., Mol. Cell. Biol.
  • RONTALIZUMAB   IFNA1

    Interaction Score: 14.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • IMIQUIMOD   IFNA1

    Interaction Score: 7.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    7534379


    Sources:
    NCI

  • DITIOCARB   IFNA1

    Interaction Score: 4.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1691765


    Sources:
    NCI

  • METYROSINE   IFNA1

    Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    7685917


    Sources:
    NCI

  • Ensembl: ENSG00000197919

    • Version: 101_38

    Alternate Names:
    IFNA1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TTD: Interferon alpha

    • Version: 2020.06.01

    Alternate Names:
    IFNA TTD Gene Abbreviation
    T45598 TTD Target ID

    Gene Info:

    Publications:
    Lichtman EI et al., 2012, Emerging therapies for systemic lupus erythematosus--focus on targeting interferon-alpha., Clin Immunol

  • NCI: IFNA1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Calvert et al., 1990, Effects of the copper chelators diethyldithiocarbamate and bathocuproine sulfonate on interferon and its antiviral state., J. Interferon Res.
    Won et al., 1993, Alpha-methyl-p-tyrosine reduces poly I:C-induced augmenting interferon production and splenic natural killer cell activity in mice., Pharmacology
    Yano et al., 2005, Expression and activation of apoptosis-related molecules involved in interferon-alpha-mediated apoptosis in human liver cancer cells., Int. J. Oncol.

  • HingoraniCasas: ENSG00000197919

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000197919 Gene Symbol
    IFNA1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • Pharos: IFNA1

    • Version: 03-September-2020

    Alternate Names:
    Interferon alpha-1/13 Gene Name
    P01562 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, ENZYME

    Publications:

  • TTD: Interferon

    • Version: 2020.06.01

    Alternate Names:
    IFN TTD Gene Abbreviation
    T73671 TTD Target ID

    Gene Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21