• Interaction Score: 6.55

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Inhibitor of nuclear factor kappa B kinase beta subunit inhibitor
    Direct Interaction yes

    PMIDs:
    21896960


  • Interaction Score: 4.37

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Inhibitor of nuclear factor kappa B kinase beta subunit inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 4.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19093800


    Sources:
    DTC

  • Interaction Score: 4.37

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Inhibitor of nuclear factor kappa B kinase beta subunit inhibitor

    PMIDs:
    None found


  • Interaction Score: 4.37

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name MLN-0415
    Novel drug target Established target
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 3.64

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

  • Interaction Score: 2.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18702457


    Sources:
    DTC

  • Interaction Score: 2.18

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Inhibitor of nuclear factor kappa B kinase beta subunit inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 2.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18088098


    Sources:
    DTC

  • Interaction Score: 2.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18088098


    Sources:
    DTC

  • Interaction Score: 1.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17407812


    Sources:
    DrugBank

  • Interaction Score: 1.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Inhibitor of nuclear factor kappa B kinase beta subunit inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 1.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.66

    Interaction Types & Directionality:
    allosteric modulator

    Interaction Info:
    Specific Action of the Ligand Negative
    Endogenous Drug? False
    Direct Interaction? True

    PMIDs:
    18702457


  • Interaction Score: 0.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 0.52

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name SPD476,Lialda
    Novel drug target Established target

  • Interaction Score: 0.24

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Inhibitor of nuclear factor kappa B kinase beta subunit inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.23

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:


    Sources:
    DrugBank

  • Interaction Score: 0.17

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    10788610


    Sources:
    DrugBank

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    31664190


    Sources:
    PharmGKB

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 0.01

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    26516587


    Sources:
    DrugBank