• Interaction Score: 14.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21295473


    Sources:
    DTC

  • Interaction Score: 7.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 3.54

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name AVN-944
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 1.18

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor

    PMIDs:
    None found


  • Interaction Score: 1.07

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction <i>In vitro</i> inhibition of IMPDH (isoform not specified, human and mouse assayed)
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

  • Interaction Score: 0.89

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor

    PMIDs:
    None found


  • Interaction Score: 0.69

    Interaction Types & Directionality:
    n/a

    Interaction Info:

  • Interaction Score: 0.55

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor
    Direct Interaction yes
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found