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IMPDH2 3615 Druggable Genome
Alternate Names:
3615 INOSINE MONOPHOSPHATE DEHYDROGENASE 2 IMPDH2 IMPD2 IMPDH-II 146691 6053 ENSG00000178035 OTTHUMG00000156771 PA29863 P12268 IMPD 2 Inosine-5'-monophosphate dehydrogenase 2 IMP dehydrogenase 2 IMPDH 2 IMDH2_HUMAN INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2 (EC 1.1.1.205) (IMP DEHYDROGENASE 2) (IMPDH-II) (IMPD 2). [SOURCE:UNIPROT/SWISSPROT;ACC:P12268] T89360 Gene Info:
Target Main Class Enzymes Target Subclass 1.1.1.205 Uniprot Evidence 1: Evidence at protein level Interpro Short Name IMP_DH_GMPRt Interpro Acc IPR001093 Interpro Name IMP dehydrogenase/GMP reductase Uniprot Status Swiss-Prot Interpro Type Domain Human Readable Name DRUGGABLE GENOME Target Class Enzymes Target Subclass EC:1.1.1.205 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
DRUGGABLE GENOME ENZYME Publications:
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Interaction Score: 17.67
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Interaction Score: 4.42
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor Direct Interaction yes -
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name AVN-944 Novel drug target Established target -
Interaction Score: 1.47
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor -
Interaction Score: 1.1
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor -
Interaction Score: 0.85
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Interaction Score: 0.34
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor Direct Interaction yes
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- Version: 101_38
Alternate Names:
IMPDH2 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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Alternate Names:
ENSG00000178035 Ensembl Gene Id IMDH2_HUMAN Uniprot Id 3615 Entrez Gene Id Gene Info:
Target Main Class Enzymes Target Subclass 1.1.1.205 Publications:
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- Version: 11-September-2012
Alternate Names:
P12268 Uniprot Accession INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2 Uniprot Protein Name IMPDH2 Uniprot Gene Name Gene Info:
Uniprot Evidence 1: Evidence at protein level Interpro Short Name IMP_DH_GMPRt Interpro Acc IPR001093 Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 26-July-2011
Alternate Names:
ENSG00000178035 Ensembl Gene Id INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2 (EC 1.1.1.205) (IMP DEHYDROGENASE 2) (IMPDH-II) (IMPD 2). [SOURCE:UNIPROT/SWISSPROT;ACC:P12268] Description IMPDH2 Display Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: January-2014
Alternate Names:
IMPDH2 Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:1.1.1.205 Publications:
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Alternate Names:
PA29863 PharmGKB ID Gene Info:
Publications:
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Alternate Names:
Gene Info:
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- Version: 31-May-2017
Alternate Names:
ENSG00000178035 Gene Symbol IMPDH2 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
IMPD2 GENE_SYMBOL IMPDH2 GENE_SYMBOL Inosine-5'-monophosphate dehydrogenase 2 UNIPROT Gene Info:
Publications:
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- Version: 2020.06.01
Alternate Names:
IMPDH2 TTD Gene Abbreviation T89360 TTD Target ID Gene Info:
Publications:
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Alternate Names:
Inosine-5'-monophosphate dehydrogenase 2 Gene Name P12268 UniProt ID Gene Info:
Gene Categories:
ENZYME Publications: