• ITPR1 3708 Druggable Genome

    Alternate Names:

    3708
    INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 1
    ITPR1
    ACV
    CLA4
    INSP3R1
    IP3R
    IP3R1
    PPP1R94
    SCA15
    SCA16
    SCA29
    147265
    6180
    ENSG00000150995
    OTTHUMG00000154996
    Q14643
    INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR
    ITPR1_HUMAN
    INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 1 (TYPE 1 INOSITOL 1,4,5- TRISPHOSPHATE RECEPTOR) (TYPE 1 INSP3 RECEPTOR) (IP3 RECEPTOR ISOFORM 1) (INSP3R1) (IP3R). [SOURCE:UNIPROT/SWISSPROT;ACC:Q14643]
    743
    IP<sub>3</sub>R1
    ITPR
    T82624

    Gene Info:

    Human Readable Name ION CHANNEL
    Interpro Short Name Ion_trans_dom
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Ion transport domain
    Uniprot Status Swiss-Prot
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR005821
    Interpro Type Domain
    Initial Gene Query IP3R1
    Counted Citations from 1950-2000 917
    GuideToPharmacology Gene Category ID 123
    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name IP<sub>3</sub> receptors
    (5 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    KINASE
    ION CHANNEL
    DRUGGABLE GENOME
  • Interaction Score: 7.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 1.42

    Interaction Types & Directionality:
    antagonist (inhibitory)
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Details of Interaction mM range
    Endogenous Drug? False

    PMIDs:
    1844813


  • Interaction Score: 1.25

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Interaction Context cytosolic
    Specific Action of the Ligand None
    Details of Interaction < mM range

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    ITPR1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: February-2014

    Alternate Names:
    3708 Entrez Gene ID

    Gene Info:
    Initial Gene Query IP3R1
    Counted Citations from 1950-2000 917

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 1 (TYPE 1 INOSITOL 1,4,5- TRISPHOSPHATE RECEPTOR) (TYPE 1 INSP3 RECEPTOR) (IP3 RECEPTOR ISOFORM 1) (INSP3R1) (IP3R). [SOURCE:UNIPROT/SWISSPROT;ACC:Q14643] Description
    ENSG00000150995 Ensembl Gene Id
    ITPR1 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    ITPR1 Uniprot Gene Name
    ENSG00000150995 Ensembl Gene Id
    INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 1 Uniprot Protein Name

    Gene Info:
    Human Readable Name ION CHANNEL
    Interpro Short Name Ion_trans_dom
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    6180 HUGO Gene ID
    6180 HUGO Gene Symbol
    inositol 1,4,5-trisphosphate receptor type 1 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name IP<sub>3</sub> receptors
    GuideToPharmacology Gene Category ID 123

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000150995 Gene Symbol
    ITPR1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000150995 Ensembl Gene ID
    ACV Human Protein Atlas Gene Synonym
    Insp3r1 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    TRANSPORTER

    Publications:

  • Alternate Names:
    ITPR TTD Gene Abbreviation
    T82624 TTD Target ID

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Inositol 1,4,5-trisphosphate receptor type 1 Gene Name
    Q14643 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, ION CHANNEL

    Publications: