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KAT2B Gene Record

  • Summary
  • Interactions
  • Claims
  • KAT2B 8850 Druggable Genome

    Alternate Names:

    8850
    LYSINE ACETYLTRANSFERASE 2B
    KAT2B
    CAF
    P/CAF
    PCAF
    602303
    8638
    ENSG00000114166
    OTTHUMG00000130481
    Q92831
    PA162392705
    GCN5
    GCN5L

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME

    Publications:

    Filippakopoulos et al., 2012, Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family., Bioorg. Med. Chem.
    Milite C et al., 2011, Modulation of the activity of histone acetyltransferases by long chain alkylidenemalonates (LoCAMs)., Bioorg Med Chem
    Ghizzoni M et al., 2010, Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative., Bioorg Med Chem
    Sbardella G et al., 2008, Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases., Bioorg Med Chem Lett
  • CHEMBL1797709   KAT2B

    Interaction Score: 11.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21292492


    Sources:
    DTC

  • CHEMBL404916   KAT2B

    Interaction Score: 8.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18434144 21292492


    Sources:
    DTC

  • CHEMBL1797711   KAT2B

    Interaction Score: 5.62

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21292492


    Sources:
    DTC

  • CHEMBL1797707   KAT2B

    Interaction Score: 3.75

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21292492


    Sources:
    DTC

  • CHEMBL416038   KAT2B

    Interaction Score: 3.75

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20655754


    Sources:
    DTC

  • CHEMBL257748   KAT2B

    Interaction Score: 3.75

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21292492


    Sources:
    DTC

  • CHEMBL1797708   KAT2B

    Interaction Score: 3.75

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21292492


    Sources:
    DTC

  • NABIXIMOLS   KAT2B

    Interaction Score: 1.87

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • AMPHETAMINE   KAT2B

    Interaction Score: 0.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • TRIAZOLAM   KAT2B

    Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22137933


    Sources:
    DTC

  • COCAINE   KAT2B

    Interaction Score: 0.27

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • Ensembl: ENSG00000114166

    • Version: 101_38

    Alternate Names:
    KAT2B Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • DTC: KAT2B

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Filippakopoulos et al., 2012, Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family., Bioorg. Med. Chem.
    Milite C et al., 2011, Modulation of the activity of histone acetyltransferases by long chain alkylidenemalonates (LoCAMs)., Bioorg Med Chem
    Ghizzoni M et al., 2010, Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative., Bioorg Med Chem

  • HingoraniCasas: ENSG00000114166

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000114166 Gene Symbol
    KAT2B Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • PharmGKB: KAT2B

    • Version: 18-August-2020

    Alternate Names:
    PA162392705 PharmGKB ID

    Gene Info:

    Publications:

  • HumanProteinAtlas: KAT2B

    • Version: 19.3

    Alternate Names:
    ENSG00000114166 Ensembl Gene ID
    GCN5 Human Protein Atlas Gene Synonym
    GCN5L Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21