• KCNH1 3756 Druggable Genome

    Alternate Names:

    3756
    POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1
    KCNH1
    EAG
    EAG1
    Kv10.1
    TMBTS
    ZLS1
    h-eag
    hEAG1
    603305
    6250
    ENSG00000143473
    OTTHUMG00000036309
    EAG channel 1
    Voltage-gated potassium channel subunit Kv10.1
    Ether-a-go-go potassium channel 1
    KCNH1_HUMAN
    O95259
    POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1 (VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT KV10.1) (ETHER-A-GO-GO POTASSIUM CHANNEL 1) (HEAG1) (H-EAG). [SOURCE:UNIPROT/SWISSPROT;ACC:O95259]
    570
    NP_758872|NP_002229
    NM_172362|NM_002238
    K<SUB>v</SUB>10.1
    hEAG

    Gene Info:

    Initial Gene Query Kv10.1
    Counted Citations from 1950-2000 832
    Human Readable Name DRUGGABLE GENOME
    GuideToPharmacology Gene Category Name Voltage-gated potassium channels
    GuideToPharmacology Gene Category ID 81
    Uniprot Status Swiss-Prot
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name ION CHANNEL
    Interpro Type Domain
    Interpro Short Name Ion_trans_dom
    Interpro Acc IPR005821
    Interpro Name Ion transport domain
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    ION CHANNEL
    DRUGGABLE GENOME
  • Interaction Score: 5.32

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 1.33

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.82

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    PMIDs:
    15365094


  • Interaction Score: 0.76

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    PMIDs:
    15365094


  • Interaction Score: 0.44

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.35

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.28

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.14

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated potassium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.14

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated potassium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.12

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated potassium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.11

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Mechanism of Interaction Voltage-gated potassium channel blocker
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.07

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    KCNH1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: February-2014

    Alternate Names:
    3756 Entrez Gene ID

    Gene Info:
    Initial Gene Query Kv10.1
    Counted Citations from 1950-2000 832

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    O95259 Uniprot Accession
    KCNH1 Uniprot Gene Name
    POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1 Uniprot Protein Name

    Gene Info:
    Uniprot Status Swiss-Prot
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name ION CHANNEL

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000143473 Ensembl Gene Id
    KCNH1 Display Id
    POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1 (VOLTAGE-GATED POTASSIUM CHANNEL SUBUNIT KV10.1) (ETHER-A-GO-GO POTASSIUM CHANNEL 1) (HEAG1) (H-EAG). [SOURCE:UNIPROT/SWISSPROT;ACC:O95259] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    6250 HUGO Gene ID
    6250 HUGO Gene Symbol
    potassium voltage-gated channel subfamily H member 1 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Voltage-gated potassium channels
    GuideToPharmacology Gene Category ID 81

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000143473 Gene Symbol
    KCNH1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    EAG1 GENE_SYMBOL
    KCNH1 GENE_SYMBOL
    Potassium voltage-gated channel subfamily H member 1 UNIPROT

    Gene Info:

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000143473 Ensembl Gene ID
    eag Human Protein Atlas Gene Synonym
    eag1 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    TRANSPORTER, ION CHANNEL

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Potassium voltage-gated channel subfamily H member 1 Gene Name
    O95259 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: