• Interaction Score: 9.97

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Novel drug target Established target
    Trial Name -

  • Interaction Score: 7.97

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 1.99

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Mechanism of Interaction Sulfonylurea receptors; K-ATP channels opener
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 1.99

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Mechanism of Interaction Sulfonylurea receptors; K-ATP channels opener
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 1.0

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand None

    PMIDs:
    None found


  • Interaction Score: 0.72

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Mechanism of Interaction Potassium channel, inwardly rectifying, subfamily J, member 8 opener
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.44

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    KCNJ8 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: February-2014

    Alternate Names:
    3764 Entrez Gene ID

    Gene Info:
    Initial Gene Query Kir6.1
    Counted Citations from 1950-2000 247

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    KCNJ8 Display Id
    ENSG00000121361 Ensembl Gene Id
    ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 8 (POTASSIUM CHANNEL, INWARDLY RECTIFYING, SUBFAMILY J, MEMBER 8) (INWARDLY RECTIFIER K(+) CHANNEL KIR6.1) (UKATP-1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15842] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: January-2014

    Alternate Names:
    KCNJ8 Gene Symbol

    Gene Info:
    Target Class Transporters
    Target Subclass TC:1.A.2.1

    Publications:

    • Version: 01-August-2011

    Alternate Names:
    ENSG00000121361 Ensembl Gene Id
    Q15842 Uniprot Accession
    KCNJ8 Gene Symbol

    Gene Info:
    Target Main Class Transporters
    Target Subclass InwardlyRectifyingKchannel
    Target Subclass Channels

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    6269 HUGO Gene ID
    6269 HUGO Gene Symbol
    potassium inwardly rectifying channel subfamily J member 8 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Inwardly rectifying potassium channels
    GuideToPharmacology Gene Category ID 74

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: chembl_23

    Alternate Names:
    KCNJ8 GENE_SYMBOL
    ATP-sensitive inward rectifier potassium channel 8 UNIPROT
    Inward rectifier K(+) channel Kir6.1 UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000121361 Gene Symbol
    KCNJ8 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    ATP-sensitive inward rectifier potassium channel 8 Gene Name
    Q15842 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: