• Interaction Score: 12.76

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24561669


    Sources:
    DTC

  • Interaction Score: 3.19

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 2.66

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

  • Interaction Score: 2.13

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction studied at 1-5 mM
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.44

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Specific Action of the Ligand None
    Details of Interaction studied at 1-5 mM
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.41

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Mechanism of Interaction Potassium channel subfamily K member 2 opener
    Direct Interaction yes
    Specific Action of the Ligand None

    PMIDs:
    None found


  • Interaction Score: 0.28

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Specific Action of the Ligand None
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Mechanism of Interaction Potassium channel subfamily K member 2 opener
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Mechanism of Interaction Potassium channel subfamily K member 2 opener
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Mechanism of Interaction Potassium channel subfamily K member 2 opener
    Direct Interaction yes

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    KCNK2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: February-2014

    Alternate Names:
    3776 Entrez Gene ID

    Gene Info:
    Initial Gene Query K2p2.1
    Counted Citations from 1950-2000 251

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 01-August-2011

    Alternate Names:
    3776 Entrez Gene Id
    KCNK2_HUMAN Uniprot Id
    O95069 Uniprot Accession

    Gene Info:
    Target Subclass Two-p_K_channels
    Transmembrane Helix Count 6
    Target Subclass Voltage_gated_ion_channels

    Publications:

    • Version: January-2014

    Alternate Names:
    KCNK2 Gene Symbol

    Gene Info:
    Target Class Transporters
    Target Subclass TC:1.A.1.8

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    6277 HUGO Gene ID
    6277 HUGO Gene Symbol
    potassium two pore domain channel subfamily K member 2 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Two P domain potassium channels
    GuideToPharmacology Gene Category ID 79

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 02-September-2020
    • Version: chembl_23

    Alternate Names:
    TREK1 GENE_SYMBOL
    KCNK2 GENE_SYMBOL
    Potassium channel subfamily K member 2 UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000082482 Gene Symbol
    KCNK2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    TREK GO Gene Synonym
    TREK1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    CELL SURFACE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Potassium channel subfamily K member 2 Gene Name
    O95069 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: