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LPAR2 Gene Record

  • Summary
  • Interactions
  • Claims
  • LPAR2 9170 Druggable Genome

    Alternate Names:

    9170
    LYSOPHOSPHATIDIC ACID RECEPTOR 2
    LPAR2
    EDG-4
    EDG4
    LPA-2
    LPA2
    605110
    3168
    ENSG00000064547
    OTTHUMG00000182328
    Q9HBW0
    LPAR2_HUMAN
    LYSOPHOSPHATIDIC ACID RECEPTOR EDG-4 (LPA RECEPTOR 2) (LPA-2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9HBW0]

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Interpro Acc IPR000276
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name GPCR, rhodopsin-like, 7TM
    Uniprot Status Swiss-Prot
    Interpro Type Family
    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    CELL SURFACE
    G PROTEIN COUPLED RECEPTOR
    DRUGGABLE GENOME

    Publications:

    Seo et al., 1999, Caffeine does not inhibit substance P-evoked intracellular Ca2+ mobilization in rat salivary acinar cells., Am. J. Physiol.
    Groer et al., 2007, An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization., Mol. Pharmacol.
    Cervia et al., 2008, Modulation of the neuronal response to ischaemia by somatostatin analogues in wild-type and knock-out mouse retinas., J. Neurochem.
  • OCTREOTIDE   LPAR2

    Interaction Score: 4.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18624922


    Sources:
    NCI

  • CAFFEINE   LPAR2

    Interaction Score: 1.53

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10199823


    Sources:
    NCI

  • MORPHINE   LPAR2

    Interaction Score: 1.33

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17090705


    Sources:
    NCI

  • Ensembl: ENSG00000064547

    • Version: 101_38

    Alternate Names:
    LPAR2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: Q9HBW0

    • Version: 11-September-2012

    Alternate Names:
    9170 Entrez Gene Id
    LPAR2 Uniprot Gene Name
    Q9HBW0 Uniprot Accession

    Gene Info:
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Interpro Acc IPR000276
    Interpro Short Name 7TM_GPCR_Rhodpsn

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000064547

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000064547 Ensembl Gene Id
    EDG4 Display Id
    LYSOPHOSPHATIDIC ACID RECEPTOR EDG-4 (LPA RECEPTOR 2) (LPA-2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9HBW0] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • NCI: LPAR2

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Seo et al., 1999, Caffeine does not inhibit substance P-evoked intracellular Ca2+ mobilization in rat salivary acinar cells., Am. J. Physiol.
    Groer et al., 2007, An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization., Mol. Pharmacol.
    Cervia et al., 2008, Modulation of the neuronal response to ischaemia by somatostatin analogues in wild-type and knock-out mouse retinas., J. Neurochem.

  • HingoraniCasas: ENSG00000064547

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000064547 Gene Symbol
    LPAR2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: LPAR2

    • Version: 01-February-2022

    Alternate Names:
    EDG4 GO Gene Synonym
    LPA2 GO Gene Synonym

    Gene Info:

    Gene Categories:
    CELL SURFACE, G PROTEIN COUPLED RECEPTOR

    Publications:

  • dGene: LPAR2

    • Version: 27-Jun-2013

    Alternate Names:
    9170 Gene ID
    EDG-4 dGene Synonym
    EDG4 dGene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21