• MAP2K4 6416 Druggable GenomeClinically Actionable

    Alternate Names:

    6416
    MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4
    MAP2K4
    JNKK
    JNKK1
    MAPKK4
    MEK4
    MKK4
    PRKMK4
    SAPKK-1
    SAPKK1
    SEK1
    SERK1
    SKK1
    601335
    6844
    ENSG00000065559
    OTTHUMG00000178267
    2065
    P45985
    DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4
    MP2K4_HUMAN
    DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 (EC 2.7.1.37) (EC 2.7.1.112) (MAP KINASE KINASE 4) (JNK ACTIVATING KINASE 1) (C-JUN N-TERMINAL KINASE KINASE 1) (JNKK) (SAPK/ERK KINASE 1) (SEK1). [SOURCE:UNIPROT/SWISSPROT;ACC:P45985]
    NM_003010
    NP_003001
    PA30589

    Gene Info:

    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Interpro Type Domain
    Human Readable Name KINASE
    Interpro Acc IPR002290
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Target Class Enzymes
    Target Subclass EC:2.7.12.2
    GuideToPharmacology Gene Category Name STE7 family
    GuideToPharmacology Gene Category ID 623
    Gene Biotype PROTEIN_CODING
    (12 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE
    ENZYME

    Publications:

    • Version: 101_38

    Alternate Names:
    MAP2K4 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: January-2014

    Alternate Names:
    MAP2K4 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.12.2

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 (EC 2.7.1.37) (EC 2.7.1.112) (MAP KINASE KINASE 4) (JNK ACTIVATING KINASE 1) (C-JUN N-TERMINAL KINASE KINASE 1) (JNKK) (SAPK/ERK KINASE 1) (SEK1). [SOURCE:UNIPROT/SWISSPROT;ACC:P45985] Description
    ENSG00000065559 Ensembl Gene Id
    MAP2K4 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000065559 Ensembl Gene Id
    MP2K4_HUMAN Uniprot Id
    P45985 Uniprot Accession

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    6844 HUGO Gene ID
    6844 HUGO Gene Symbol
    mitogen-activated protein kinase kinase 4 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name STE7 family
    GuideToPharmacology Gene Category ID 623

    Gene Categories:
    ENZYME

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000065559 Gene Symbol
    MAP2K4 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 18-August-2020

    Alternate Names:
    PA30589 PharmGKB ID

    Gene Info:

    Publications:

    • Version: 11-November-2018

    Alternate Names:
    MAP2K4 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    6416 Gene ID
    JNKK dGene Synonym
    JNKK1 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    JNKK1 GO Gene Synonym
    MEK4 GO Gene Synonym
    MKK4 GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE, TYROSINE KINASE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Dual specificity mitogen-activated protein kinase kinase 4 Gene Name
    P45985 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

    • Version: 30-February-2014

    Alternate Names:

    Gene Info:

    Publications:

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

    • Version: v3

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: