• MAPKAPK5 8550 Druggable Genome

    Alternate Names:

    8550
    MITOGEN-ACTIVATED PROTEIN KINASE-ACTIVATED PROTEIN KINASE 5
    MAPKAPK5
    MAPKAP-K5
    MK-5
    MK5
    PRAK
    606723
    6889
    ENSG00000089022
    OTTHUMG00000169605
    MAP KINASE-ACTIVATED PROTEIN KINASE 5 (EC 2.7.1.37) (MAPK-ACTIVATED PROTEIN KINASE 5) (MAPKAP KINASE 5) (P38-REGULATED/ACTIVATED PROTEIN KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8IW41]
    Q8IW41
    MAPK5_HUMAN
    MAP KINASE-ACTIVATED PROTEIN KINASE 5
    2096
    NP_003659
    NM_003668
    MAPKAPK-5
    MAPKAP kinase 5
    MAPK-activated protein kinase 5
    p38-regulated/activated protein kinase
    MAPK activated protein kinase 5

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Interpro Type Domain
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR002290
    Human Readable Name KINASE
    Target Class Enzymes
    Target Subclass EC:2.7.11.1
    GuideToPharmacology Gene Category Name MAPKAPK subfamily
    GuideToPharmacology Gene Category ID 512
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • Interaction Score: 63.79

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction MAP kinase-activated protein kinase 5 inhibitor
    Direct Interaction yes
    Trial Name GLPG0259

    PMIDs:
    None found


  • Interaction Score: 0.82

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

    • Version: 101_38

    Alternate Names:
    MAPKAPK5 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    MAP KINASE-ACTIVATED PROTEIN KINASE 5 (EC 2.7.1.37) (MAPK-ACTIVATED PROTEIN KINASE 5) (MAPKAP KINASE 5) (P38-REGULATED/ACTIVATED PROTEIN KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8IW41] Description
    MAPKAPK5 Display Id
    ENSG00000089022 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    8550 Entrez Gene Id
    MAPK5_HUMAN Uniprot Id
    MAP KINASE-ACTIVATED PROTEIN KINASE 5 Uniprot Protein Name

    Gene Info:
    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Interpro Type Domain

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: January-2014

    Alternate Names:
    MAPKAPK5 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.1

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    6889 HUGO Gene ID
    6889 HUGO Gene Symbol
    MAPK activated protein kinase 5 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name MAPKAPK subfamily
    GuideToPharmacology Gene Category ID 512

    Gene Categories:
    ENZYME

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000089022 Gene Symbol
    MAPKAPK5 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    PRAK GENE_SYMBOL
    MAPKAPK5 GENE_SYMBOL
    MAP kinase-activated protein kinase 5 UNIPROT

    Gene Info:

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    8550 Gene ID
    MAPKAP-K5 dGene Synonym
    MK-5 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    PRAK GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    MAP kinase-activated protein kinase 5 Gene Name
    Q8IW41 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: