• METAP2 10988 Druggable Genome

    Alternate Names:

    10988
    METHIONYL AMINOPEPTIDASE 2
    METAP2
    MAP2
    MNPEP
    p67eIF2
    601870
    16672
    ENSG00000111142
    OTTHUMG00000170280
    Methionine aminopeptidase 2
    MetAP 2
    p67
    MAP 2
    Peptidase M
    Initiation factor 2-associated 67 kDa glycoprotein
    P50579
    1573
    NM_006838
    NP_006829
    AMPM2_HUMAN
    METHIONINE AMINOPEPTIDASE 2 (EC 3.4.11.18) (METAP 2) (PEPTIDASE M 2) (INITIATION FACTOR 2 ASSOCIATED 67 KDA GLYCOPROTEIN) (P67) (P67EIF2). [SOURCE:UNIPROT/SWISSPROT;ACC:P50579]
    T75596

    Gene Info:

    Target Class Enzymes
    Target Subclass EC:3.4.11.18
    GuideToPharmacology Gene Category Name M24: Methionyl aminopeptidase
    GuideToPharmacology Gene Category ID 746
    Human Readable Name PROTEASE
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Domain
    Interpro Name Peptidase M24, structural domain
    Uniprot Status Swiss-Prot
    Interpro Acc IPR000994
    Interpro Short Name Pept_M24_structural-domain
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    KINASE
    PROTEASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • Interaction Score: 63.79

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name ZGN-433
    Novel drug target Novel Target
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found


  • Interaction Score: 42.53

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Novel drug target Novel Target
    Trial Name PPI-2458

    PMIDs:
    None found


  • Interaction Score: 1.12

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Aminopeptidases inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    METAP2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: January-2014

    Alternate Names:
    METAP2 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:3.4.11.18

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    AMPM2_HUMAN Uniprot Id
    10988 Entrez Gene Id
    METAP2 Uniprot Gene Name

    Gene Info:
    Human Readable Name PROTEASE
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    PROTEASE, DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000111142 Ensembl Gene Id
    METAP2 Display Id
    METHIONINE AMINOPEPTIDASE 2 (EC 3.4.11.18) (METAP 2) (PEPTIDASE M 2) (INITIATION FACTOR 2 ASSOCIATED 67 KDA GLYCOPROTEIN) (P67) (P67EIF2). [SOURCE:UNIPROT/SWISSPROT;ACC:P50579] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    16672 HUGO Gene ID
    16672 HUGO Gene Symbol
    methionyl aminopeptidase 2 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name M24: Methionyl aminopeptidase
    GuideToPharmacology Gene Category ID 746

    Gene Categories:
    ENZYME

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000111142 Gene Symbol
    METAP2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    P67EIF2 GENE_SYMBOL
    METAP2 GENE_SYMBOL
    Methionine aminopeptidase 2 UNIPROT

    Gene Info:

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    10988 Gene ID
    MAP2 dGene Synonym
    MNPEP dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    METAP2 TTD Gene Abbreviation
    T75596 TTD Target ID

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Methionine aminopeptidase 2 Gene Name
    P50579 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications: