MKNK2 Gene Record

  • MKNK2 2872 Druggable Genome

    Alternate Names:

    2872
    MAP KINASE INTERACTING SERINE/THREONINE KINASE 2
    MKNK2
    GPRK7
    MNK2
    605069
    7111
    ENSG00000099875
    OTTHUMG00000180020
    Q9HBH9
    MKNK2_HUMAN
    MAP KINASE-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2
    MAP KINASE-INTERACTING SERINE/THREONINE KINASE 2 (EC 2.7.1.37) (MAP KINASE SIGNAL-INTEGRATING KINASE 2) (MNK2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9HBH9]
    MAPK interacting serine/threonine kinase 2
    MAP kinase signal-integrating kinase 2
    T99160

    Gene Info:

    Uniprot Evidence 1: Evidence at protein level
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR002290
    Interpro Type Domain
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Uniprot Status Swiss-Prot
    Human Readable Name KINASE
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME

    Publications:

  • TOMIVOSERTIB   MKNK2

    Interaction Score: 1.29

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • CHEMBL541400   MKNK2

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SNS-314   MKNK2

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GSK-269962A   MKNK2

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ERLOTINIB   MKNK2

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL225519   MKNK2

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GEFITINIB   MKNK2

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • LINIFANIB   MKNK2

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • R-406   MKNK2

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SORAFENIB   MKNK2

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RG-1530   MKNK2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SP-600125   MKNK2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CYC-116   MKNK2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TAE-684   MKNK2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ILORASERTIB   MKNK2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CENISERTIB   MKNK2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000099875

    • Version: 101_38

    Alternate Names:
    MKNK2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000099875

    • Version: 26-July-2011

    Alternate Names:
    MKNK2 Display Id
    ENSG00000099875 Ensembl Gene Id
    MAP KINASE-INTERACTING SERINE/THREONINE KINASE 2 (EC 2.7.1.37) (MAP KINASE SIGNAL-INTEGRATING KINASE 2) (MNK2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9HBH9] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: Q9HBH9

    • Version: 11-September-2012

    Alternate Names:
    MKNK2_HUMAN Uniprot Id
    2872 Entrez Gene Id
    ENSG00000099875 Ensembl Gene Id

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • HingoraniCasas: ENSG00000099875

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000099875 Gene Symbol
    MKNK2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • IDG: MKNK2

    • Version: 15-July-2019

    Alternate Names:
    MKNK2 Gene Symbol

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • GO: MKNK2

    • Version: 01-February-2022

    Alternate Names:
    GPRK7 GO Gene Synonym
    MNK2 GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

  • dGene: MKNK2

    • Version: 27-Jun-2013

    Alternate Names:
    2872 Gene ID
    GPRK7 dGene Synonym
    MNK2 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • TTD: MAP kinase signal-integrating kinase 2

    • Version: 2020.06.01

    Alternate Names:
    MKNK2 TTD Gene Abbreviation
    T99160 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: MKNK2

    • Version: 01-February-2022

    Alternate Names:
    MAP kinase-interacting serine/threonine-protein kinase 2 Gene Name
    Q9HBH9 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • DTC: MKNK2

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: