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MMP2 4313 Druggable Genome
Alternate Names:
4313 MATRIX METALLOPEPTIDASE 2 MMP2 CLG4 CLG4A MMP-2 MMP-II MONA TBE-1 120360 7166 ENSG00000087245 OTTHUMG00000133202 P08253 72 KDA TYPE IV COLLAGENASE MATRIX METALLOPROTEINASE-2 MMP2_HUMAN 72 KDA TYPE IV COLLAGENASE PRECURSOR (EC 3.4.24.24) (72 KDA GELATINASE) (MATRIX METALLOPROTEINASE-2) (MMP-2) (GELATINASE A) (TBE- 1). [SOURCE:UNIPROT/SWISSPROT;ACC:P08253] 1629 NP_001121363|NP_004521 NM_001127891|NM_004530 3549 T68251 Gene Info:
Target Main Class Enzymes Target Subclass 3.4.24.24 Uniprot Evidence 1: Evidence at protein level Interpro Name Peptidase, metallopeptidase Interpro Type Domain Interpro Acc IPR006026 Uniprot Status Swiss-Prot Human Readable Name DRUGGABLE GENOME Human Readable Name PROTEASE Interpro Short Name Peptidase_Metallo GuideToPharmacology Gene Category Name M10: Matrix metallopeptidase GuideToPharmacology Gene Category ID 738 Target Class Enzymes Target Subclass EC:3.4.24.24 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
NEUTRAL ZINC METALLOPEPTIDASE PROTEASE DRUGGABLE GENOME ENZYME Publications:
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Interaction Score: 4.73
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Interaction Score: 3.38
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Novel drug target Novel Target Trial Name - Specific Action of the Ligand Inhibition
Sources:
TdgClinicalTrial TEND GuideToPharmacology TTD -
Interaction Score: 2.36
Interaction Types & Directionality:
n/a Interaction Info:
Novel drug target Novel Target Trial Name COL-3,Metastat -
Interaction Score: 2.36
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False -
Interaction Types & Directionality:
vaccine (activating) Interaction Info:
Notes -
Interaction Score: 0.95
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Interaction Score: 0.79
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Interaction Score: 0.68
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Interaction Score: 0.43
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Interaction Score: 0.36
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Interaction Score: 0.34
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Interaction Score: 0.3
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False -
Interaction Score: 0.25
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Interaction Score: 0.18
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Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction? False Endogenous Drug? False Specific Action of the Ligand Inhibition -
Interaction Score: 0.15
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Interaction Score: 0.14
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Interaction Score: 0.14
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Interaction Score: 0.1
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Interaction Score: 0.1
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Interaction Score: 0.09
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Interaction Score: 0.08
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Interaction Score: 0.05
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- Version: 101_38
Alternate Names:
MMP2 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 26-July-2011
Alternate Names:
72 KDA TYPE IV COLLAGENASE PRECURSOR (EC 3.4.24.24) (72 KDA GELATINASE) (MATRIX METALLOPROTEINASE-2) (MMP-2) (GELATINASE A) (TBE- 1). [SOURCE:UNIPROT/SWISSPROT;ACC:P08253] Description MMP2 Display Id ENSG00000087245 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
4313 Entrez Gene Id P08253 Uniprot Accession MMP2_HUMAN Uniprot Id Gene Info:
Target Subclass 3.4.24.24 Target Main Class Enzymes Publications:
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- Version: 11-September-2012
Alternate Names:
MMP2_HUMAN Uniprot Id ENSG00000087245 Ensembl Gene Id 72 KDA TYPE IV COLLAGENASE Uniprot Protein Name Gene Info:
Uniprot Evidence 1: Evidence at protein level Interpro Name Peptidase, metallopeptidase Interpro Type Domain Gene Categories:
PROTEASE, DRUGGABLE GENOME Publications:
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- Version: January-2014
Alternate Names:
MMP2 Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:3.4.24.24 Publications:
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- Version: 29-September-2020
Alternate Names:
7166 HUGO Gene ID 7166 HUGO Gene Symbol matrix metallopeptidase 2 HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name M10: Matrix metallopeptidase GuideToPharmacology Gene Category ID 738 Gene Categories:
ENZYME Publications:
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Alternate Names:
4313 Entrez Gene ID 3549 CIViC Gene ID Gene Info:
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Alternate Names:
Gene Info:
Publications:
-
Alternate Names:
Gene Info:
Publications:
-
Alternate Names:
MMP-2 Gene Symbol Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000087245 Gene Symbol MMP2 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
-
Alternate Names:
MMP2 Gene Symbol Gene Info:
Publications:
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Alternate Names:
4313 Gene ID CLG4 dGene Synonym CLG4A dGene Synonym Gene Info:
Gene Categories:
PROTEASE Publications:
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- Version: 2020.06.01
Alternate Names:
MMP-2 TTD Gene Abbreviation T68251 TTD Target ID Gene Info:
Publications:
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Alternate Names:
CLG4A GO Gene Synonym Gene Info:
Gene Categories:
NEUTRAL ZINC METALLOPEPTIDASE Publications:
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Alternate Names:
72 kDa type IV collagenase Gene Name P08253 UniProt ID Gene Info:
Gene Categories:
ENZYME Publications: