MMP8 Gene Record

  • MMP8 4317 Druggable Genome

    Alternate Names:

    4317
    MATRIX METALLOPEPTIDASE 8
    MMP8
    CLG1
    HNC
    MMP-8
    PMNL-CL
    120355
    7175
    ENSG00000118113
    OTTHUMG00000167587
    P22894
    MMP8_HUMAN
    PMNL COLLAGENASE
    NEUTROPHIL COLLAGENASE
    MATRIX METALLOPROTEINASE-8
    NEUTROPHIL COLLAGENASE PRECURSOR (EC 3.4.24.34) (MATRIX METALLOPROTEINASE-8) (MMP-8) (PMNL COLLAGENASE) (PMNL-CL). [SOURCE:UNIPROT/SWISSPROT;ACC:P22894]
    T08856

    Gene Info:

    Human Readable Name PROTEASE
    Target Class Enzymes
    Target Subclass EC:3.4.24.34
    Uniprot Status Swiss-Prot
    Interpro Acc IPR006026
    Interpro Name Peptidase, metallopeptidase
    Interpro Short Name Peptidase_Metallo
    Interpro Type Domain
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    PROTEASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • CIPEMASTAT   MMP8

    Interaction Score: 6.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • DOXYCYCLINE CALCIUM   MMP8

    Interaction Score: 3.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Matrix metalloproteinase 8 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DOXYCYCLINE   MMP8

    Interaction Score: 3.09

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Matrix metalloproteinase 8 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DOXYCYCLINE HYCLATE   MMP8

    Interaction Score: 1.55

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Matrix metalloproteinase 8 inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • COLLAGENASE CLOSTRIDIUM HISTOLYTICUM   MMP8

    Interaction Score: 0.44

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name Cordase
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Ensembl: ENSG00000118113

    • Version: 101_38

    Alternate Names:
    MMP8 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: P22894

    • Version: January-2014

    Alternate Names:
    MMP8 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:3.4.24.34

    Publications:

  • HopkinsGroom: P22894

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000118113 Ensembl Gene Id
    4317 Entrez Gene Id
    MMP8_HUMAN Uniprot Id

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Acc IPR006026
    Human Readable Name PROTEASE

    Gene Categories:
    PROTEASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000118113

    • Version: 26-July-2011

    Alternate Names:
    NEUTROPHIL COLLAGENASE PRECURSOR (EC 3.4.24.34) (MATRIX METALLOPROTEINASE-8) (MMP-8) (PMNL COLLAGENASE) (PMNL-CL). [SOURCE:UNIPROT/SWISSPROT;ACC:P22894] Description
    MMP8 Display Id
    ENSG00000118113 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: CLG1

    • Version: chembl_23

    Alternate Names:
    CLG1 GENE_SYMBOL
    MMP8 GENE_SYMBOL
    Neutrophil collagenase UNIPROT

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000118113

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000118113 Gene Symbol
    MMP8 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: MMP8

    • Version: 01-February-2022

    Alternate Names:
    CLG1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

  • dGene: MMP8

    • Version: 27-Jun-2013

    Alternate Names:
    4317 Gene ID
    CLG1 dGene Synonym
    HNC dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

  • TTD: Matrix metalloproteinase-8

    • Version: 2020.06.01

    Alternate Names:
    MMP-8 TTD Gene Abbreviation
    T08856 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: MMP8

    • Version: 01-February-2022

    Alternate Names:
    Neutrophil collagenase Gene Name
    P22894 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications: