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MYOD1 Gene Record

  • Summary
  • Interactions
  • Claims
  • MYOD1 4654 Clinically Actionable

    Alternate Names:

    4654
    MYOGENIC DIFFERENTIATION 1
    MYOD1
    MYF3
    MYOD
    PUM
    bHLHc1
    159970
    7611
    ENSG00000129152
    OTTHUMG00000166358
    MYODRIF
    P15172
    Myoblast determination protein 1

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    TRANSCRIPTION FACTOR COMPLEX
    CLINICALLY ACTIONABLE
    TRANSCRIPTION FACTOR

    Publications:

    Summan et al., 2006, Macrophages and skeletal muscle regeneration: a clodronate-containing liposome depletion study., Am. J. Physiol. Regul. Integr. Comp. Physiol.
    Singh et al., 2003, Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway., Endocrinology
    Kurabayashi et al., 1994, Doxorubicin represses the function of the myogenic helix-loop-helix transcription factor MyoD. Involvement of Id gene induction., J. Biol. Chem.
    Busson et al., 2006, Avian MyoD and c-Jun coordinately induce transcriptional activity of the 3,5,3'-triiodothyronine nuclear receptor c-ErbAalpha1 in proliferating myoblasts., Endocrinology
    Kvorning et al., 2007, Suppression of testosterone does not blunt mRNA expression of myoD, myogenin, IGF, myostatin or androgen receptor post strength training in humans., J. Physiol. (Lond.)
    Yun et al., 2005, Differential effects of Hsp90 inhibition on protein kinases regulating signal transduction pathways required for myoblast differentiation., Exp. Cell Res.
    Kimura et al., 2008, Cell-lineage regulated myogenesis for dystrophin replacement: a novel therapeutic approach for treatment of muscular dystrophy., Hum. Mol. Genet.
    Suga et al., 2001, Interleukin-11 induces osteoblast differentiation and acts synergistically with bone morphogenetic protein-2 in C3H10T1/2 cells., J. Interferon Cytokine Res.
    Tanaka et al., 2008, Expression of mRNA for specific fibroblast growth factors associates with that of the myogenic markers MyoD and proliferating cell nuclear antigen in regenerating and overloaded rat plantaris muscle., Acta Physiol (Oxf)
  • OPRELVEKIN   MYOD1

    Interaction Score: 2.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11576464


    Sources:
    NCI

  • GOSERELIN   MYOD1

    Interaction Score: 2.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17095559


    Sources:
    NCI

  • BUPIVACAINE   MYOD1

    Interaction Score: 1.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18429950


    Sources:
    NCI

  • CLODRONIC ACID   MYOD1

    Interaction Score: 1.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16424086


    Sources:
    NCI

  • GELDANAMYCIN   MYOD1

    Interaction Score: 0.98

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15922741


    Sources:
    NCI

  • ANDROSTANOLONE   MYOD1

    Interaction Score: 0.6

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12960001


    Sources:
    NCI

  • LIOTHYRONINE SODIUM   MYOD1

    Interaction Score: 0.46

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16556763


    Sources:
    NCI

  • TAMOXIFEN   MYOD1

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18511457


    Sources:
    NCI

  • DOXORUBICIN   MYOD1

    Interaction Score: 0.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8119948


    Sources:
    NCI

  • Ensembl: ENSG00000129152

    • Version: 101_38

    Alternate Names:
    MYOD1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: MYOD1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Busson et al., 2006, Avian MyoD and c-Jun coordinately induce transcriptional activity of the 3,5,3'-triiodothyronine nuclear receptor c-ErbAalpha1 in proliferating myoblasts., Endocrinology
    Kimura et al., 2008, Cell-lineage regulated myogenesis for dystrophin replacement: a novel therapeutic approach for treatment of muscular dystrophy., Hum. Mol. Genet.
    Vaidya et al., 1989, Fibroblast growth factor and transforming growth factor beta repress transcription of the myogenic regulatory gene MyoD1., Mol. Cell. Biol.

  • GO: MYOD1

    • Version: 01-February-2022

    Alternate Names:
    BHLHC1 GO Gene Synonym
    MYF3 GO Gene Synonym
    MYOD GO Gene Synonym

    Gene Info:

    Gene Categories:
    TRANSCRIPTION FACTOR COMPLEX

    Publications:

  • Pharos: MYOD1

    • Version: 01-February-2022

    Alternate Names:
    Myoblast determination protein 1 Gene Name
    P15172 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSCRIPTION FACTOR

    Publications:

  • MskImpact: MYOD1

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21