• Interaction Score: 0.45

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family Farnesyltransferase inhibitor
    Alteration NF1:del
    Alteration NF1:.

    PMIDs:
    None found


    Sources:
    CGI

  • Interaction Score: 0.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Alteration NF1:.
    Drug family MEK inhibitor
    Alteration NF1:del

  • Interaction Score: 0.4

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family MTOR inhibitor;VEGFR inhibitor
    combination therapy Everolimus;Pazopanib
    Drug family MTOR inhibitor;EGFR inhibitor 1st gen


    Sources:
    CGI

  • Interaction Score: 0.39

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


  • Interaction Score: 0.39

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family MEK inhibitor
    Alteration NF1:del
    Alteration NF1:.

  • Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

  • Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family BRAF inhibitor
    Alteration NF1:.
    Alteration NF1:del;BRAF:.

    PMIDs:
    23288408 231718


    Sources:
    CGI CIViC

  • Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


  • Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23171796


    Sources:
    CIViC

  • Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family BCR-ABL inhibitor 2nd gen
    Alteration NF1:del
    Alteration NF1:.

    PMIDs:
    None found


    Sources:
    CGI

  • Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family Pan-TK inhibitor
    Alteration NF1:del
    Alteration NF1:.

    PMIDs:
    None found


    Sources:
    CGI

  • Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Alteration NF1:.
    Alteration NF1:del
    Drug family VEGFR mAb inhibitor

    PMIDs:
    2485933 24232489


    Sources:
    CGI

  • Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family MTOR inhibitor
    Alteration NF1:del
    Alteration NF1:.

    PMIDs:
    23171796


    Sources:
    CGI CIViC

  • Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family Chemotherapy;BCR-ABL inhibitor 2nd gen
    combination therapy Vinblastine;Nilotinib
    Alteration NF1:.

    PMIDs:
    None found


    Sources:
    CGI

  • Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy Everolimus;Pazopanib
    Drug family MTOR inhibitor;VEGFR inhibitor
    Alteration NF1:.

    PMIDs:
    None found


    Sources:
    CGI

  • Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family ALK inhibitor
    Alteration NF1:del
    Alteration NF1:.

    PMIDs:
    None found


    Sources:
    CGI

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family EGFR inhibitor 1st gen
    Alteration NF1:del
    Alteration NF1:.

    PMIDs:
    None found


    Sources:
    CGI

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Alteration NF1:.
    Alteration NF1:del
    Drug family Hormonal therapy

    PMIDs:
    None found


    Sources:
    CGI

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family BCR-ABL inhibitor 1st gen&KIT inhibitor
    Alteration NF1:del
    Alteration NF1:.

    PMIDs:
    None found


    Sources:
    CGI

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Drug family BCR-ABL inhibitor 2nd gen
    Alteration NF1:del
    Alteration NF1:.

    PMIDs:
    None found


    Sources:
    CGI

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy Sorafenib;Sirolimus
    Drug family Pan-TK inhibitor;MTOR inhibitor
    Alteration NF1:del

    PMIDs:
    None found


    Sources:
    CGI