• NLRP3 114548 Druggable Genome

    Alternate Names:

    114548
    NLR FAMILY PYRIN DOMAIN CONTAINING 3
    NLRP3
    AGTAVPRL
    AII
    AVP
    C1orf7
    CIAS1
    CLR1.1
    FCAS
    FCAS1
    FCU
    MWS
    NALP3
    PYPAF1
    606416
    16400
    ENSG00000162711
    OTTHUMG00000040647
    Q96P20
    1770
    Caterpiller protein 1.1
    T08499

    Gene Info:

    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name NOD-like receptor family
    GuideToPharmacology Gene Category ID 317
    (3 More Sources)

    Gene Categories: Category Details

    TRANSCRIPTION FACTOR BINDING
    DRUGGABLE GENOME
  • Interaction Score: 12.62

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction As assessed by inhibition of recombinant NLRP3 ATPase activity by dapansutrile.
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 6.31

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 6.31

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 1.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    14872505


    Sources:
    NCI

  • Interaction Score: 0.9

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.9

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.79

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.79

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC