• Search
      • Search Interactions Search Categories
    • Browse
      • Browse Categories Browse Sources
    • Information
      • About Publications Interaction Types & Directionalities Interaction Score & Query Score API Documentation FAQ Known Data Clients News Contact
    • Downloads
      • Data Source Code

NPPA Gene Record

  • Summary
  • Interactions
  • Claims
  • NPPA 4878 Druggable Genome

    Alternate Names:

    4878
    NATRIURETIC PEPTIDE A
    NPPA
    ANF
    ANP
    ATFB6
    ATRST2
    CDD
    CDD-ANF
    CDP
    PND
    108780
    7939
    ENSG00000175206
    OTTHUMG00000002388
    PA256

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    HORMONE ACTIVITY
    DRUGGABLE GENOME

    Publications:

    Lynch AI et al., 2008, Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension., JAMA
  • CHLORTHALIDONE   NPPA

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18212314


    Sources:
    PharmGKB

  • AMLODIPINE   NPPA

    Interaction Score: 5.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18212314


    Sources:
    PharmGKB

  • Ensembl: ENSG00000175206

    • Version: 101_38

    Alternate Names:
    NPPA Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • PharmGKB: NPPA

    • Version: 18-August-2020

    Alternate Names:
    PA256 PharmGKB ID

    Gene Info:

    Publications:
    Lynch AI et al., 2008, Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension., JAMA

  • NCI: NPPA

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Montilla et al., [Effect of cyclosporin A, azathioprine, and methylprednisolone on plasma levels and heart atrial content of atrial natriuretic peptide in the rat]., Minerva Endocrinol.
    Pouta et al., 1996, Pre-eclampsia: the effect of intravenous fluid preload on atrial natriuretic peptide secretion during caesarean section under spinal anaesthesia., Acta Anaesthesiol Scand

  • HingoraniCasas: ENSG00000175206

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000175206 Gene Symbol
    NPPA Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: NPPA

    • Version: 01-February-2022

    Alternate Names:
    ANP GO Gene Synonym
    PND GO Gene Synonym

    Gene Info:

    Gene Categories:
    HORMONE ACTIVITY

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21