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NPY Gene Record

  • Summary
  • Interactions
  • Claims
  • NPY 4852 Druggable Genome

    Alternate Names:

    4852
    NEUROPEPTIDE Y
    NPY
    PYY4
    162640
    7955
    ENSG00000122585
    OTTHUMG00000022973
    P01303
    Pro-neuropeptide Y

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    KINASE
    G PROTEIN COUPLED RECEPTOR
    HORMONE ACTIVITY
    DRUGGABLE GENOME

    Publications:

    Bernet et al., 1998, Circulating neuropeptide Y (NPY) and catecholamines in rat under resting and stress conditions. Arguments for extra-adrenal origin of NPY, adrenal and extra-adrenal sources of catecholamines., Neurosci. Lett.
    Foucart et al., 1990, Inhibition of noradrenaline release by neuropeptide Y does not involve protein kinase C in mouse atria., Neuropeptides
    Obuchowicz et al., 2005, Alterations in striatal neuropeptide Y system activity of rats with haloperidol-induced behavioral supersensitivity., Neuropeptides
    Pelletier et al., 1991, Dopaminergic regulation of pre-proNPY mRNA levels in the rat arcuate nucleus., Neurosci. Lett.
    Wang et al., 1997, Increased feeding in fatty Zucker rats by the thiazolidinedione BRL 49653 (rosiglitazone) and the possible involvement of leptin and hypothalamic neuropeptide Y., Br. J. Pharmacol.
  • K-252A   NPY

    Interaction Score: 12.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2259391


    Sources:
    NCI

  • ETHER   NPY

    Interaction Score: 4.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9696062


    Sources:
    NCI

  • BROMOCRIPTINE   NPY

    Interaction Score: 1.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1679226


    Sources:
    NCI

  • ROSIGLITAZONE   NPY

    Interaction Score: 1.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9421288


    Sources:
    NCI

  • HALOPERIDOL   NPY

    Interaction Score: 0.39

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16154634


    Sources:
    NCI

  • Ensembl: ENSG00000122585

    • Version: 101_38

    Alternate Names:
    NPY Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: NPY

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Bernet et al., 1998, Circulating neuropeptide Y (NPY) and catecholamines in rat under resting and stress conditions. Arguments for extra-adrenal origin of NPY, adrenal and extra-adrenal sources of catecholamines., Neurosci. Lett.
    McAuley et al., 1992, Central cardiovascular effects of rilmenidine and neuropeptide Y in the conscious spontaneously hypertensive rat: haemodynamic and biochemical evidence for a negative interaction., J. Cardiovasc. Pharmacol.
    Poncet et al., 1991, Clonidine but not propranolol decreases plasma neuropeptide Y (NPY) levels., Fundam Clin Pharmacol

  • HingoraniCasas: ENSG00000122585

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000122585 Gene Symbol
    NPY Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • Pharos: NPY

    • Version: 01-February-2022

    Alternate Names:
    Pro-neuropeptide Y Gene Name
    P01303 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • GO: NPY

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR, HORMONE ACTIVITY

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21