4985 |
OPIOID RECEPTOR DELTA 1 |
OPRD1 |
OPRD |
165195 |
8153 |
ENSG00000116329 |
OTTHUMG00000003646 |
P41143 |
OPRD_HUMAN |
D-OR-1 |
Delta-type opioid receptor |
DOR-1 |
DELTA-TYPE OPIOID RECEPTOR (DOR-1). [SOURCE:UNIPROT/SWISSPROT;ACC:P41143] |
PA31942 |
Opioid receptor delta |
T58992 |
DOP |
DOR |
DOR1 |
Human Readable Name | G PROTEIN COUPLED RECEPTOR |
Transmembrane Helix Count | 7 |
Target Main Class | Receptors |
Target Subclass | Rhodopsin |
Target Subclass | GPCR |
Human Readable Name | DRUGGABLE GENOME |
Interpro Acc | IPR000276 |
Interpro Short Name | 7TM_GPCR_Rhodpsn |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Name | GPCR, rhodopsin-like, 7TM |
Interpro Type | Family |
Uniprot Status | Swiss-Prot |
Target Class | Receptors |
Gene Biotype | PROTEIN_CODING |
G PROTEIN COUPLED RECEPTOR |
DRUGGABLE GENOME |
antagonist (inhibitory) |
Mechanism of Interaction | Opioid receptors; mu/kappa/delta antagonist |
Direct Interaction | yes |
Trial Name | ALO-01, morphine sulfate and naltrexone hydrochloride,Embeda, Kadian NT |
agonist (activating) |
antagonist (inhibitory) |
Trial Name | nalmefene, CPH-101 |
Novel drug target | Established target |
agonist (activating) |
Trial Name | ADL5747 |
Novel drug target | Established target |
agonist (activating) |
antagonist (inhibitory) |
Trial Name | nalbuphine hydrochloride, PW-4142 |
Novel drug target | Established target |
Trial Name | REN-213 |
antagonist (inhibitory) |
Trial Name | oxymorphone hydrochloride, EN3202,Opana, Opana ER |
Novel drug target | Established target |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
agonist (activating) |
Trial Name | sufentanil transdermal patch,Transdur-sufentanil |
Novel drug target | Established target |
Trial Name | sufentanil,Chronogesic |
agonist (activating) |
Trial Name | transmucosal fentanyl,Actiq |
Trial Name | fentanyl transdermal system,Duragesic, Ionsys |
Trial Name | fentanyl sublingual spray |
antagonist (inhibitory) |
Mechanism of Interaction | Opioid receptors; mu/kappa/delta antagonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Opioid receptors; mu/kappa/delta agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Opioid receptors; mu/kappa/delta agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Opioid receptors; mu/kappa/delta agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Opioid receptors; mu/kappa/delta agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Opioid receptors; mu/kappa/delta agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Opioid receptors; mu/kappa/delta agonist |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Opioid receptors; mu/kappa/delta antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Opioid receptors; mu/kappa/delta antagonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Opioid receptors; mu/kappa/delta agonist |
n/a |
Trial Name | KP201 (prodrug of hydrocodone) |
Novel drug target | Established target |
agonist (activating) |
Mechanism of Interaction | Delta opioid receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Trial Name | ALO-01, morphine sulfate and naltrexone hydrochloride,Embeda, Kadian NT |
Novel drug target | Established target |
Trial Name | intranasal morphine,Rylomine |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Opioid receptors; mu/kappa/delta agonist |
antagonist (inhibitory) |
Mechanism of Interaction | Opioid receptors; mu/kappa/delta antagonist |
Direct Interaction | yes |
OPRD1 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
OPRD1 | Display Id |
ENSG00000116329 | Ensembl Gene Id |
DELTA-TYPE OPIOID RECEPTOR (DOR-1). [SOURCE:UNIPROT/SWISSPROT;ACC:P41143] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
P41143 | Uniprot Accession |
OPRD_HUMAN | Uniprot Id |
4985 | Entrez Gene Id |
Transmembrane Helix Count | 7 |
Target Main Class | Receptors |
Target Subclass | Rhodopsin |
DELTA-TYPE OPIOID RECEPTOR | Uniprot Protein Name |
OPRD1 | Uniprot Gene Name |
P41143 | Uniprot Accession |
Human Readable Name | DRUGGABLE GENOME |
Interpro Acc | IPR000276 |
Interpro Short Name | 7TM_GPCR_Rhodpsn |
G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME |
OPRD1 | Gene Symbol |
Target Subclass | Rhodopsin |
Target Class | Receptors |
Target Subclass | GPCR |
PA31942 | PharmGKB ID |
OPRD1 | TTD Gene Abbreviation |
T58992 | TTD Target ID |
OPRD | GENE_SYMBOL |
OPRD1 | GENE_SYMBOL |
Delta-type opioid receptor | UNIPROT |
ENSG00000116329 | Gene Symbol |
OPRD1 | Ensembl Id |
DRUGGABLE GENOME |
OPRD | GO Gene Synonym |
G PROTEIN COUPLED RECEPTOR |
4985 | Gene ID |
OPRD | dGene Synonym |
G PROTEIN COUPLED RECEPTOR |