• P2RX3 5024 Druggable Genome

    Alternate Names:

    5024
    PURINERGIC RECEPTOR P2X 3
    P2RX3
    P2X3
    600843
    8534
    ENSG00000109991
    OTTHUMG00000167025
    P56373
    P2X PURINOCEPTOR 3
    P2RX3_HUMAN
    ATP receptor
    Purinergic receptor
    P2X PURINOCEPTOR 3 (ATP RECEPTOR) (P2X3) (PURINERGIC RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P56373]
    480
    NP_002550
    NM_002559
    T17140

    Gene Info:

    Uniprot Status Swiss-Prot
    Interpro Name P2X purinoreceptor
    Uniprot Evidence 2: Evidence at transcript level
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Family
    Interpro Short Name P2X_purnocptor
    Interpro Acc IPR001429
    GuideToPharmacology Gene Category Name P2X receptors
    GuideToPharmacology Gene Category ID 77
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    ION CHANNEL
    DRUGGABLE GENOME

    Publications:

  • Interaction Score: 38.28

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction P2X purinoceptor 3 antagonist
    Direct Interaction yes
    Specific Action of the Ligand Antagonist

    PMIDs:
    None found


  • Interaction Score: 6.38

    Interaction Types & Directionality:
    allosteric modulator

    Interaction Info:
    Specific Action of the Ligand Negative
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 6.38

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 0.75

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Specific Action of the Ligand Agonist
    Endogenous Drug? True
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.34

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    P2RX3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    P2RX3_HUMAN Uniprot Id
    5024 Entrez Gene Id
    P56373 Uniprot Accession

    Gene Info:
    Interpro Name P2X purinoreceptor
    Uniprot Status Swiss-Prot
    Uniprot Evidence 2: Evidence at transcript level

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    P2RX3 Display Id
    P2X PURINOCEPTOR 3 (ATP RECEPTOR) (P2X3) (PURINERGIC RECEPTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P56373] Description
    ENSG00000109991 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    8534 HUGO Gene ID
    8534 HUGO Gene Symbol
    purinergic receptor P2X 3 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name P2X receptors
    GuideToPharmacology Gene Category ID 77

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000109991 Gene Symbol
    P2RX3 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    P2RX3 GENE_SYMBOL
    P2X purinoceptor 3 UNIPROT
    ATP receptor UNIPROT

    Gene Info:

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    P2RX3 TTD Gene Abbreviation
    T17140 TTD Target ID

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    P2X purinoceptor 3 Gene Name
    P56373 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: