• PAK3 5063 Druggable GenomeClinically Actionable

    Alternate Names:

    5063
    P21 (RAC1) ACTIVATED KINASE 3
    PAK3
    ARA
    MRX30
    MRX47
    OPHN3
    PAK-3
    PAK3beta
    bPAK
    beta-PAK
    300142
    8592
    ENSG00000077264
    OTTHUMG00000022202
    SERINE/THREONINE-PROTEIN KINASE PAK 3 (EC 2.7.1.37) (P21-ACTIVATED KINASE 3) (PAK-3) (BETA-PAK) (OLIGOPHRENIN-3). [SOURCE:UNIPROT/SWISSPROT;ACC:O75914]
    2135
    NM_002578
    O75914
    NP_001121638
    PAK3_HUMAN
    SERINE/THREONINE-PROTEIN KINASE PAK 3
    hPAK3
    CDKN1A

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    GuideToPharmacology Gene Category Name PAKA subfamily
    GuideToPharmacology Gene Category ID 547
    Uniprot Status Swiss-Prot
    Interpro Type Domain
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name KINASE
    Interpro Acc IPR002290
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Uniprot Evidence 1: Evidence at protein level
    Gene Biotype PROTEIN_CODING
    (9 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE
    ENZYME
  • Interaction Score: 5.32

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.8

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    19035792


    Sources:
    DTC

    • Version: 101_38

    Alternate Names:
    PAK3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000077264 Ensembl Gene Id
    PAK3 Display Id
    SERINE/THREONINE-PROTEIN KINASE PAK 3 (EC 2.7.1.37) (P21-ACTIVATED KINASE 3) (PAK-3) (BETA-PAK) (OLIGOPHRENIN-3). [SOURCE:UNIPROT/SWISSPROT;ACC:O75914] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    PAK3 Uniprot Gene Name
    SERINE/THREONINE-PROTEIN KINASE PAK 3 Uniprot Protein Name
    PAK3_HUMAN Uniprot Id

    Gene Info:
    Uniprot Status Swiss-Prot
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Domain

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    8592 HUGO Gene ID
    8592 HUGO Gene Symbol
    p21 (RAC1) activated kinase 3 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name PAKA subfamily
    GuideToPharmacology Gene Category ID 547

    Gene Categories:
    ENZYME

    Publications:

    • Version: 02-September-2020
    • Version: 31-May-2017

    Alternate Names:
    ENSG00000077264 Gene Symbol
    PAK3 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 15-July-2019

    Alternate Names:
    PAK3 Gene Symbol

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000077264 Ensembl Gene ID
    bPAK Human Protein Atlas Gene Synonym
    hPAK3 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    5063 Gene ID
    CDKN1A dGene Synonym
    MRX30 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • GO: PAK3

    • Version: 01-May-2021

    Alternate Names:
    OPHN3 GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Serine/threonine-protein kinase PAK 3 Gene Name
    O75914 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, ENZYME

    Publications:

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: