• PDE8A 5151 Druggable Genome

    Alternate Names:

    5151
    PHOSPHODIESTERASE 8A
    PDE8A
    HsT19550
    602972
    8793
    ENSG00000073417
    OTTHUMG00000148670
    O60658
    HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8A
    PDE8A_HUMAN
    HIGH-AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8A (EC 3.1.4.17). [SOURCE:UNIPROT/SWISSPROT;ACC:O60658]
    1307

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name PDEase_catalytic_dom
    Uniprot Status Swiss-Prot
    Interpro Acc IPR002073
    Interpro Name 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name Phosphodiesterases, 3',5'-cyclic nucleotide (PDEs)
    GuideToPharmacology Gene Category ID 260
    (2 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME

    Publications:

  • Interaction Score: 2.66

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Phosphodiesterase 8 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.82

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Mechanism of Interaction 3',5'-cyclic phosphodiesterase inhibitor

    PMIDs:
    None found


  • Interaction Score: 0.63

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 3',5'-cyclic phosphodiesterase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    PDE8A Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    PDE8A_HUMAN Uniprot Id
    PDE8A Uniprot Gene Name
    ENSG00000073417 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name PDEase_catalytic_dom
    Interpro Acc IPR002073

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    PDE8A Display Id
    HIGH-AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8A (EC 3.1.4.17). [SOURCE:UNIPROT/SWISSPROT;ACC:O60658] Description
    ENSG00000073417 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    8793 HUGO Gene ID
    8793 HUGO Gene Symbol
    phosphodiesterase 8A HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Phosphodiesterases, 3',5'-cyclic nucleotide (PDEs)
    GuideToPharmacology Gene Category ID 260

    Gene Categories:
    ENZYME

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000073417 Gene Symbol
    PDE8A Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    PDE8A GENE_SYMBOL
    High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A UNIPROT

    Gene Info:

    Publications: