• PDE8B 8622 Druggable Genome

    Alternate Names:

    8622
    PHOSPHODIESTERASE 8B
    PDE8B
    ADSD
    PPNAD3
    603390
    8794
    ENSG00000113231
    OTTHUMG00000102170
    HIGH-AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8B (EC 3.1.4.17) (HSPDE8B). [SOURCE:UNIPROT/SWISSPROT;ACC:O95263]
    HsPDE8B
    Cell proliferation-inducing gene 22 protein
    High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
    1308
    O95263
    PDE8B_HUMAN
    ENSG00000284762

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Interpro Name 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
    Uniprot Evidence 1: Evidence at protein level
    Interpro Short Name PDEase_catalytic_dom
    Interpro Acc IPR002073
    Interpro Type Domain
    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name Phosphodiesterases, 3',5'-cyclic nucleotide (PDEs)
    GuideToPharmacology Gene Category ID 260
    (2 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME

    Publications:

  • Interaction Score: 2.66

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Phosphodiesterase 8 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.82

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Mechanism of Interaction 3',5'-cyclic phosphodiesterase inhibitor

    PMIDs:
    None found


  • Interaction Score: 0.63

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 3',5'-cyclic phosphodiesterase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    PDE8B Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    PDE8B Display Id
    ENSG00000113231 Ensembl Gene Id
    HIGH-AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8B (EC 3.1.4.17) (HSPDE8B). [SOURCE:UNIPROT/SWISSPROT;ACC:O95263] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    PDE8B Uniprot Gene Name
    HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8B Uniprot Protein Name
    O95263 Uniprot Accession

    Gene Info:
    Uniprot Status Swiss-Prot
    Human Readable Name DRUGGABLE GENOME
    Interpro Name 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    8794 HUGO Gene ID
    8794 HUGO Gene Symbol
    phosphodiesterase 8B HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Phosphodiesterases, 3',5'-cyclic nucleotide (PDEs)
    GuideToPharmacology Gene Category ID 260

    Gene Categories:
    ENZYME

    Publications:

    • Version: chembl_23

    Alternate Names:
    PDE8B GENE_SYMBOL
    High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B UNIPROT
    Cell proliferation-inducing gene 22 protein UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000113231 Gene Symbol
    PDE8B Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications: