• PKN1 5585 Druggable GenomeClinically Actionable

    Alternate Names:

    5585
    PROTEIN KINASE N1
    PKN1
    DBK
    PAK-1
    PAK1
    PKN
    PKN-ALPHA
    PRK1
    PRKCL1
    601032
    9405
    ENSG00000123143
    OTTHUMG00000039611
    Q16512
    1520
    PKN1_HUMAN
    SERINE/THREONINE-PROTEIN KINASE N1
    PKC
    NP_002732
    NM_002741
    PROTEIN KINASE N1 (EC 2.7.1.37) (PROTEIN KINASE C-LIKE 1) (PROTEIN- KINASE C-RELATED KINASE 1) (PROTEIN KINASE C-LIKE PKN) (SERINE- THREONINE PROTEIN KINASE N). [SOURCE:UNIPROT/SWISSPROT;ACC:Q16512]
    BE0009520

    Gene Info:

    Target Class Enzymes
    Target Subclass EC:2.7.11.13
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR002290
    Uniprot Status Swiss-Prot
    Human Readable Name KINASE
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Type Domain
    GuideToPharmacology Gene Category Name Protein kinase N (PKN) family
    GuideToPharmacology Gene Category ID 601
    Gene Biotype PROTEIN_CODING
    (8 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE
    ENZYME
  • Interaction Score: 1.58

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.26

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.14

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • Interaction Score: 0.1

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    26516587


    Sources:
    DrugBank

    • Version: 101_38

    Alternate Names:
    PKN1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: January-2014

    Alternate Names:
    PKN1 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.13

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    PKN1 Display Id
    PROTEIN KINASE N1 (EC 2.7.1.37) (PROTEIN KINASE C-LIKE 1) (PROTEIN- KINASE C-RELATED KINASE 1) (PROTEIN KINASE C-LIKE PKN) (SERINE- THREONINE PROTEIN KINASE N). [SOURCE:UNIPROT/SWISSPROT;ACC:Q16512] Description
    ENSG00000123143 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    SERINE/THREONINE-PROTEIN KINASE N1 Uniprot Protein Name
    PKN1_HUMAN Uniprot Id
    5585 Entrez Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    9405 HUGO Gene ID
    9405 HUGO Gene Symbol
    protein kinase N1 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Protein kinase N (PKN) family
    GuideToPharmacology Gene Category ID 601

    Gene Categories:
    ENZYME

    Publications:

    • Version: 5.1.7
    • Version: 31-May-2017

    Alternate Names:
    ENSG00000123143 Gene Symbol
    PKN1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 20-Jun-2017

    Alternate Names:
    5585 Entrez Gene Id
    PKN1 MyCancerGenome Gene Symbol
    PKC MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

    • Version: 03-September-2020

    Alternate Names:
    Serine/threonine-protein kinase N1 Gene Name
    Q16512 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • GO: PKN1

    • Version: 05-September-2020

    Alternate Names:
    PAK1 GO Gene Synonym
    PKN GO Gene Synonym
    PRK1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    5585 Gene ID
    DBK dGene Synonym
    PAK-1 dGene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE, KINASE

    Publications:

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: