PKN2 Gene Record

  • PKN2 5586 Druggable Genome

    Alternate Names:

    5586
    PROTEIN KINASE N2
    PKN2
    PAK2
    PRK2
    PRKCL2
    PRO2042
    Pak-2
    STK7
    602549
    9406
    ENSG00000065243
    OTTHUMG00000010074
    PKC
    PROTEIN KINASE N2 (EC 2.7.1.37) (PROTEIN KINASE C-LIKE 2) (PROTEIN- KINASE C-RELATED KINASE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q16513]
    Q16513
    PKN2_HUMAN
    SERINE/THREONINE-PROTEIN KINASE N2
    1521
    NP_006247
    NM_006256
    BE0009521

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR002290
    Interpro Type Domain
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Human Readable Name KINASE
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    GuideToPharmacology Gene Category Name Protein kinase N (PKN) family
    GuideToPharmacology Gene Category ID 601
    Target Class Enzymes
    Target Subclass EC:2.7.11.13
    Gene Biotype PROTEIN_CODING
    (8 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • LY-2090314   PKN2

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL541400   PKN2

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GSK-269962A   PKN2

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL379975   PKN2

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ALSTERPAULLONE   PKN2

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ERLOTINIB   PKN2

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SOTRASTAURIN   PKN2

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ENTRECTINIB   PKN2

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GW441756X   PKN2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL225519   PKN2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TOZASERTIB   PKN2

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DASATINIB   PKN2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RG-1530   PKN2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DOVITINIB   PKN2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CYC-116   PKN2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TAE-684   PKN2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PF-00562271   PKN2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   PKN2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • ILORASERTIB   PKN2

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CENISERTIB   PKN2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • FOSTAMATINIB   PKN2

    Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    26516587


    Sources:
    DrugBank

  • Ensembl: ENSG00000065243

    • Version: 101_38

    Alternate Names:
    PKN2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: Q16513

    • Version: 11-September-2012

    Alternate Names:
    Q16513 Uniprot Accession
    SERINE/THREONINE-PROTEIN KINASE N2 Uniprot Protein Name
    PKN2 Uniprot Gene Name

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Human Readable Name KINASE

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000065243

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000065243 Ensembl Gene Id
    PKN2 Display Id
    PROTEIN KINASE N2 (EC 2.7.1.37) (PROTEIN KINASE C-LIKE 2) (PROTEIN- KINASE C-RELATED KINASE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:Q16513] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TdgClinicalTrial: Q16513

    • Version: January-2014

    Alternate Names:
    PKN2 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.13

    Publications:

  • GuideToPharmacology: 5586

    • Version: 29-September-2020

    Alternate Names:
    9406 HUGO Gene ID
    9406 HUGO Gene Symbol
    protein kinase N2 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Protein kinase N (PKN) family
    GuideToPharmacology Gene Category ID 601

    Gene Categories:
    ENZYME

    Publications:

  • DrugBank: BE0009521

    • Version: 5.1.7

    Alternate Names:
    PKN2 DrugBank Gene Name
    Q16513 UniProt Accession
    5586 Entrez Gene Id

    Gene Info:

    Publications:
    Rolf MG et al., 2015, In vitro pharmacological profiling of R406 identifies molecular targets underlying the clinical effects of fostamatinib., Pharmacol Res Perspect

  • MyCancerGenome: PKN2

    • Version: 20-Jun-2017

    Alternate Names:
    5586 Entrez Gene Id
    PKN2 MyCancerGenome Gene Symbol
    PKC MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000065243

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000065243 Gene Symbol
    PKN2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • Pharos: PKN2

    • Version: 03-September-2020

    Alternate Names:
    Serine/threonine-protein kinase N2 Gene Name
    Q16513 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • GO: PKN2

    • Version: 05-September-2020

    Alternate Names:
    PRK2 GO Gene Synonym
    PRKCL2 GO Gene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • dGene: PKN2

    • Version: 27-Jun-2013

    Alternate Names:
    5586 Gene ID
    PAK2 dGene Synonym
    PRK2 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • DTC: PKN2

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: