• Search
      • Search Interactions Search Categories
    • Browse
      • Browse Categories Browse Sources
    • Information
      • About Publications Interaction Types & Directionalities Interaction Score & Query Score API Documentation FAQ Known Data Clients News Contact
    • Downloads
      • Data Source Code

PLA2G4A Gene Record

  • Summary
  • Interactions
  • Claims
  • PLA2G4A 5321 Druggable Genome

    Alternate Names:

    5321
    PHOSPHOLIPASE A2 GROUP IVA
    PLA2G4A
    PLA2G4
    cPLA2
    cPLA2-alpha
    600522
    9035
    ENSG00000116711
    OTTHUMG00000035512
    P47712
    PA24A_HUMAN
    PA271
    Cytosolic phospholipase A2
    GIVA cPLA2
    T14834
    GURDP

    Gene Info:

    Target Main Class Enzymes
    Target Subclass 3.1.1.4
    Target Subclass 3.1.1.5
    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME

    Publications:

    Ayuso P et al., 2015, Association study of genetic variants in PLA2G4A, PLCG1, LAT, SYK, and TNFRS11A genes in NSAIDs-induced urticaria and/or angioedema patients., Pharmacogenet Genomics
  • FLUOCINONIDE   PLA2G4A

    Interaction Score: 2.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TEND

  • FLURANDRENOLIDE   PLA2G4A

    Interaction Score: 2.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TEND

  • FLUOROMETHOLONE   PLA2G4A

    Interaction Score: 2.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TEND

  • MEDRYSONE   PLA2G4A

    Interaction Score: 1.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TEND

  • FLUNISOLIDE   PLA2G4A

    Interaction Score: 0.69

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TEND

  • DICLOFENAC   PLA2G4A

    Interaction Score: 0.65

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26398624


    Sources:
    PharmGKB

  • ACETAMINOPHEN   PLA2G4A

    Interaction Score: 0.35

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26398624


    Sources:
    PharmGKB

  • ATENOLOL   PLA2G4A

    Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • ASPIRIN   PLA2G4A

    Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26398624


    Sources:
    PharmGKB

  • Ensembl: ENSG00000116711

    • Version: 101_38

    Alternate Names:
    PLA2G4A Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TEND: P47712

    • Version: 01-August-2011

    Alternate Names:
    PA24A_HUMAN Uniprot Id
    PLA2G4A Gene Symbol
    P47712 Uniprot Accession

    Gene Info:
    Target Main Class Enzymes
    Target Subclass 3.1.1.4
    Target Subclass 3.1.1.5

    Publications:

  • PharmGKB: PLA2G4A

    • Version: 18-August-2020

    Alternate Names:
    PA271 PharmGKB ID

    Gene Info:

    Publications:
    Ayuso P et al., 2015, Association study of genetic variants in PLA2G4A, PLCG1, LAT, SYK, and TNFRS11A genes in NSAIDs-induced urticaria and/or angioedema patients., Pharmacogenet Genomics

  • HingoraniCasas: ENSG00000116711

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000116711 Gene Symbol
    PLA2G4A Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TTD: Cytosolic phospholipase A2

    • Version: 2020.06.01

    Alternate Names:
    GIVA cPLA2 TTD Gene Abbreviation
    T14834 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: PLA2G4A

    • Version: 01-February-2022

    Alternate Names:
    Cytosolic phospholipase A2 Gene Name
    P47712 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21