DGIdb - PLD1 Gene Record

PLD1 5337 Druggable Genome

Alternate Names:

5337
PHOSPHOLIPASE D1
PLD1
CVDD
602382
9067
ENSG00000075651
OTTHUMG00000156947
Q13393
1433
T38996

Gene Info:

GuideToPharmacology Gene Category Name	Phosphatidylcholine-specific phospholipase D
GuideToPharmacology Gene Category ID	276
Gene Biotype	PROTEIN_CODING

(4 More Sources)

Gene Categories: Category Details

DRUGGABLE GENOME
ENZYME

Publications:

Eisen et al., 2002, Selective estrogen receptor (ER) modulators differentially regulate phospholipase D catalytic activity in ER-negative breast cancer cells., Mol. Pharmacol.
Scott SA et al., 2009, Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness., Nat Chem Biol

HALOPEMIDE PLD1

Interaction Score: 10.63

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
AFIMOXIFENE PLD1

Interaction Score: 3.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19136975

Sources:
DTC
TAMOXIFEN PLD1

Interaction Score: 1.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12237338 19136975

Sources:
DTC NCI

Ensembl: ENSG00000075651
- Version: 101_38
Alternate Names:

PLD1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
GuideToPharmacology: 5337
- Version: 29-September-2020
Alternate Names:

9067 HUGO Gene ID

9067 HUGO Gene Symbol

phospholipase D1 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name Phosphatidylcholine-specific phospholipase D

GuideToPharmacology Gene Category ID 276

Gene Categories:

ENZYME

Publications:

NCI: PLD1

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Eisen et al., 2002, Selective estrogen receptor (ER) modulators differentially regulate phospholipase D catalytic activity in ER-negative breast cancer cells., Mol. Pharmacol.

Kim et al., 1999, Phospholipase D1 is located and activated by protein kinase C alpha in the plasma membrane in 3Y1 fibroblast cell., Biochim. Biophys. Acta

DTC: PLD1
- Version: 02-September-2020
Alternate Names:

Gene Info:

Publications:

Scott SA et al., 2009, Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness., Nat Chem Biol
HingoraniCasas: ENSG00000075651
- Version: 31-May-2017
Alternate Names:

ENSG00000075651 Gene Symbol

PLD1 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
HumanProteinAtlas: PLD1
- Version: 19.3
Alternate Names:

ENSG00000075651 Ensembl Gene ID

Phospholipase D1 Human Protein Atlas Gene Description

Q13393 UniProt ID

Gene Info:

Gene Categories:

ENZYME

Publications:
TTD: Phospholipase D1
- Version: 2020.06.01
Alternate Names:

PLD1 TTD Gene Abbreviation

T38996 TTD Target ID

Gene Info:

Publications:
Pharos: PLD1
- Version: 01-May-2021
Alternate Names:

Phospholipase D1 Gene Name

Q13393 UniProt ID

Gene Info:

Gene Categories:

ENZYME

Publications:

9067	HUGO Gene ID
9067	HUGO Gene Symbol
phospholipase D1	HUGO Gene Name

ENSG00000075651	Ensembl Gene ID
Phospholipase D1	Human Protein Atlas Gene Description
Q13393	UniProt ID

PLD1	TTD Gene Abbreviation
T38996	TTD Target ID

PLD1 Gene Record

PLD1 5337 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

HALOPEMIDE PLD1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

AFIMOXIFENE PLD1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19136975

Sources: DTC

TAMOXIFEN PLD1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12237338 19136975

Sources: DTC NCI

Ensembl: ENSG00000075651

Alternate Names: PLD1 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

GuideToPharmacology: 5337

Alternate Names: 9067 HUGO Gene ID 9067 HUGO Gene Symbol phospholipase D1 HUGO Gene Name

Gene Info: GuideToPharmacology Gene Category Name Phosphatidylcholine-specific phospholipase D GuideToPharmacology Gene Category ID 276

Gene Categories: ENZYME

Publications:

NCI: PLD1

Alternate Names:

Gene Info:

DTC: PLD1

Alternate Names:

Gene Info:

Publications: Scott SA et al., 2009, Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness., Nat Chem Biol

HingoraniCasas: ENSG00000075651

Alternate Names: ENSG00000075651 Gene Symbol PLD1 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

HumanProteinAtlas: PLD1

Alternate Names: ENSG00000075651 Ensembl Gene ID Phospholipase D1 Human Protein Atlas Gene Description Q13393 UniProt ID

Gene Info:

Gene Categories: ENZYME

Publications:

TTD: Phospholipase D1

Alternate Names: PLD1 TTD Gene Abbreviation T38996 TTD Target ID

Gene Info:

Publications:

Pharos: PLD1

Alternate Names: Phospholipase D1 Gene Name Q13393 UniProt ID

Gene Info:

Gene Categories: ENZYME

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
19136975

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
12237338 19136975

Sources:
DTC NCI

Alternate Names:

PLD1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

9067 HUGO Gene ID

9067 HUGO Gene Symbol

phospholipase D1 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name Phosphatidylcholine-specific phospholipase D

GuideToPharmacology Gene Category ID 276

Gene Categories:

ENZYME

Publications:

Scott SA et al., 2009, Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness., Nat Chem Biol

Alternate Names:

ENSG00000075651 Gene Symbol

PLD1 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

ENSG00000075651 Ensembl Gene ID

Phospholipase D1 Human Protein Atlas Gene Description

Q13393 UniProt ID

Gene Categories:

ENZYME

Alternate Names:

PLD1 TTD Gene Abbreviation

T38996 TTD Target ID

Alternate Names:

Phospholipase D1 Gene Name

Q13393 UniProt ID

Gene Categories:

ENZYME