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PLD1 Gene Record

  • Summary
  • Interactions
  • Claims
  • PLD1 5337 Druggable Genome

    Alternate Names:

    5337
    PHOSPHOLIPASE D1
    PLD1
    CVDD
    602382
    9067
    ENSG00000075651
    OTTHUMG00000156947
    Q13393
    T38996

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME

    Publications:

    Eisen et al., 2002, Selective estrogen receptor (ER) modulators differentially regulate phospholipase D catalytic activity in ER-negative breast cancer cells., Mol. Pharmacol.
    Scott SA et al., 2009, Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness., Nat Chem Biol
  • HALOPEMIDE   PLD1

    Interaction Score: 10.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • AFIMOXIFENE   PLD1

    Interaction Score: 3.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    19136975


    Sources:
    DTC

  • TAMOXIFEN   PLD1

    Interaction Score: 1.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12237338 19136975


    Sources:
    DTC NCI

  • Ensembl: ENSG00000075651

    • Version: 101_38

    Alternate Names:
    PLD1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: PLD1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Eisen et al., 2002, Selective estrogen receptor (ER) modulators differentially regulate phospholipase D catalytic activity in ER-negative breast cancer cells., Mol. Pharmacol.
    Kim et al., 1999, Phospholipase D1 is located and activated by protein kinase C alpha in the plasma membrane in 3Y1 fibroblast cell., Biochim. Biophys. Acta

  • DTC: PLD1

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Scott SA et al., 2009, Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness., Nat Chem Biol

  • HingoraniCasas: ENSG00000075651

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000075651 Gene Symbol
    PLD1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HumanProteinAtlas: PLD1

    • Version: 19.3

    Alternate Names:
    ENSG00000075651 Ensembl Gene ID
    Phospholipase D1 Human Protein Atlas Gene Description
    Q13393 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • TTD: Phospholipase D1

    • Version: 2020.06.01

    Alternate Names:
    PLD1 TTD Gene Abbreviation
    T38996 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: PLD1

    • Version: 01-February-2022

    Alternate Names:
    Phospholipase D1 Gene Name
    Q13393 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21