5347 |
POLO LIKE KINASE 1 |
PLK1 |
PLK |
STPK13 |
602098 |
9077 |
ENSG00000166851 |
OTTHUMG00000096984 |
P53350 |
PLK1_HUMAN |
SERINE/THREONINE-PROTEIN KINASE PLK1 |
SERINE/THREONINE-PROTEIN KINASE PLK1 (EC 2.7.1.37) (POLO-LIKE KINASE 1) (PLK-1) (SERINE-THREONINE PROTEIN KINASE 13) (STPK13). [SOURCE:UNIPROT/SWISSPROT;ACC:P53350] |
polo-like kinase 1 |
PLK-1 |
Serine/threonine-protein kinase 13 |
T40694 |
Interpro Short Name | Ser/Thr_dual-sp_kinase_dom |
Interpro Acc | IPR002290 |
Human Readable Name | KINASE |
Human Readable Name | DRUGGABLE GENOME |
Uniprot Status | Swiss-Prot |
Interpro Name | Serine/threonine- / dual-specificity protein kinase, catalytic domain |
Interpro Type | Domain |
Uniprot Evidence | 1: Evidence at protein level |
Target Class | Enzymes |
Target Subclass | EC:2.7.11.21 |
Gene Biotype | PROTEIN_CODING |
TUMOR SUPPRESSOR |
KINASE |
SERINE THREONINE KINASE |
DRUGGABLE GENOME |
ENZYME |
TRANSCRIPTION FACTOR |
inhibitor (inhibitory) |
Notes | |
Mechanism of Interaction | Serine/threonine-protein kinase PLK1 inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase PLK1 inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Serine/threonine-protein kinase PLK1 inhibitor |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase PLK1 inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase PLK1 inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Notes | |
Mechanism of Interaction | Serine/threonine-protein kinase PLK1 inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase PLK1 inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Serine/threonine-protein kinase PLK1 inhibitor |
Direct Interaction | yes |
n/a |
Trial Name | ON 01910.Na,Estybon |
Novel drug target | Novel Target |
PLK1 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
PLK1_HUMAN | Uniprot Id |
PLK1 | Uniprot Gene Name |
ENSG00000166851 | Ensembl Gene Id |
Interpro Short Name | Ser/Thr_dual-sp_kinase_dom |
Interpro Acc | IPR002290 |
Human Readable Name | KINASE |
KINASE, DRUGGABLE GENOME |
PLK1 | Display Id |
ENSG00000166851 | Ensembl Gene Id |
SERINE/THREONINE-PROTEIN KINASE PLK1 (EC 2.7.1.37) (POLO-LIKE KINASE 1) (PLK-1) (SERINE-THREONINE PROTEIN KINASE 13) (STPK13). [SOURCE:UNIPROT/SWISSPROT;ACC:P53350] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
PLK1 | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:2.7.11.21 |
ENSG00000166851 | Gene Symbol |
PLK1 | Ensembl Id |
DRUGGABLE GENOME |
5347 | Entrez Gene Id |
PLK1 | MyCancerGenome Gene Symbol |
PLK1 | MyCancerGenome Reported Gene Name |
PLK | GENE_SYMBOL |
PLK1 | GENE_SYMBOL |
Serine/threonine-protein kinase PLK1 | UNIPROT |
PLK1 | Gene Symbol |
ENSG00000166851 | Ensembl Gene ID |
PLK | Human Protein Atlas Gene Synonym |
Polo like kinase 1 | Human Protein Atlas Gene Description |
ENZYME |
PLK | GO Gene Synonym |
TUMOR SUPPRESSOR, SERINE THREONINE KINASE |
5347 | Gene ID |
PLK | dGene Synonym |
STPK13 | dGene Synonym |
KINASE, SERINE THREONINE KINASE |
PLK1 | TTD Gene Abbreviation |
T40694 | TTD Target ID |
Serine/threonine-protein kinase PLK1 | Gene Name |
P53350 | UniProt ID |
KINASE, TRANSCRIPTION FACTOR |