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PMEL Gene Record

  • Summary
  • Interactions
  • Claims
  • PMEL 6490 Druggable Genome

    Alternate Names:

    6490
    PREMELANOSOME PROTEIN
    PMEL
    D12S53E
    ME20
    ME20-M
    ME20M
    P1
    P100
    PMEL17
    SI
    SIL
    SILV
    gp100
    155550
    10880
    ENSG00000185664
    OTTHUMG00000170573
    Gp100[209-217] peptide
    T46208
    Melanocytes lineage-specific antigen GP100
    T46128

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME

    Publications:

    McCormack E et al., 2013, Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1- and LAGE-1-positive tumors., Cancer Immunol Immunother
  • TEBENTAFUSP   PMEL

    Interaction Score: 37.87

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23263452


    Sources:
    TTD

  • Ensembl: ENSG00000185664

    • Version: 101_38

    Alternate Names:
    PMEL Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TTD: Melanocytes lineage-specific antigen GP100

    • Version: 2020.06.01

    Alternate Names:
    PMEL TTD Gene Abbreviation
    T46128 TTD Target ID

    Gene Info:

    Publications:
    Tarhini AA et al., 2012, Safety and immunogenicity of vaccination with MART-1 (26-35, 27L), gp100 (209-217, 210M), and tyrosinase (368-376, 370D) in adjuvant with PF-3512676 and GM-CSF in metastatic melanoma., J Immunother
    McCormack E et al., 2013, Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1- and LAGE-1-positive tumors., Cancer Immunol Immunother

  • NCI: SILV

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Damico et al., 2005, T-cell recognition and cytokine profile induced by melanocyte epitopes in patients with HLA-DRB1*0405-positive and -negative Vogt-Koyanagi-Harada uveitis., Invest. Ophthalmol. Vis. Sci.
    Fang et al., 2001, Regulation of tyrosinase-related protein-2 (TYRP2) in human melanocytes: relationship to growth and morphology., Pigment Cell Res.

  • HingoraniCasas: ENSG00000185664

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000185664 Gene Symbol
    PMEL Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TTD: Gp100[209-217] peptide

    • Version: 2020.06.01

    Alternate Names:
    PMEL TTD Gene Abbreviation
    T46208 TTD Target ID

    Gene Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21