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PNPLA3 Gene Record

  • Summary
  • Interactions
  • Claims
  • PNPLA3 80339

    Alternate Names:

    80339
    PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING 3
    PNPLA3
    ADPN
    C22orf20
    iPLA(2)epsilon
    609567
    18590
    ENSG00000100344
    OTTHUMG00000150555
    Q9NST1
    PA38592
    adiponutrin
    dJ796I17.1
    FLJ22012
    iPLA2epsilon

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    ENZYME

    Publications:

    Gutierrez-Camino A et al., 2017, PNPLA3 rs738409 and Hepatotoxicity in Children With B-cell Acute Lymphoblastic Leukemia: A Validation Study in a Spanish Cohort., Clin Pharmacol Ther
    Zhang Y et al., 2018, Single-nucleotide rs738409 polymorphisms in the PNPLA3 gene are strongly associated with alcoholic liver disease in Han Chinese males., Hepatol Int
  • ASPARAGINASE   PNPLA3

    Interaction Score: 1.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    28744905


    Sources:
    PharmGKB

  • PREDNISOLONE   PNPLA3

    Interaction Score: 0.82

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    28744905


    Sources:
    PharmGKB

  • VINCRISTINE   PNPLA3

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    28744905


    Sources:
    PharmGKB

  • DAUNORUBICIN   PNPLA3

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    28744905


    Sources:
    PharmGKB

  • CYCLOPHOSPHAMIDE   PNPLA3

    Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    28744905


    Sources:
    PharmGKB

  • ALCOHOL   PNPLA3

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30132178


    Sources:
    PharmGKB

  • Ensembl: ENSG00000100344

    • Version: 101_38

    Alternate Names:
    PNPLA3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • PharmGKB: PNPLA3

    • Version: 18-August-2020

    Alternate Names:
    PA38592 PharmGKB ID

    Gene Info:

    Publications:
    Gutierrez-Camino A et al., 2017, PNPLA3 rs738409 and Hepatotoxicity in Children With B-cell Acute Lymphoblastic Leukemia: A Validation Study in a Spanish Cohort., Clin Pharmacol Ther
    Zhang Y et al., 2018, Single-nucleotide rs738409 polymorphisms in the PNPLA3 gene are strongly associated with alcoholic liver disease in Han Chinese males., Hepatol Int

  • HumanProteinAtlas: PNPLA3

    • Version: 19.3

    Alternate Names:
    ENSG00000100344 Ensembl Gene ID
    adiponutrin Human Protein Atlas Gene Synonym
    ADPN Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21