• POLD1 5424 Druggable GenomeClinically Actionable

    Alternate Names:

    5424
    DNA POLYMERASE DELTA 1, CATALYTIC SUBUNIT
    POLD1
    CDC2
    CRCS10
    MDPL
    POLD
    174761
    9175
    ENSG00000062822
    OTTHUMG00000183037
    DNA polymerase subunit delta p125
    DNA polymerase delta catalytic subunit
    DNA POLYMERASE DELTA CATALYTIC SUBUNIT (EC 2.7.7.7) (DNA POLYMERASE DELTA SUBUNIT P125). [SOURCE:UNIPROT/SWISSPROT;ACC:P28340]
    P28340
    DPOD1_HUMAN

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR006133
    Interpro Type Domain
    Interpro Acc IPR006134
    Interpro Short Name DNA-dir_DNA_pol_B_exonuc
    Human Readable Name DNA DIRECTED DNA POLYMERASE
    Interpro Short Name DNA-dir_DNA_pol_B
    Interpro Type Family
    Uniprot Status Swiss-Prot
    Interpro Name DNA-directed DNA polymerase, family B, exonuclease domain
    Interpro Short Name DNA-dir_DNA_pol_B_multi_dom
    Interpro Name DNA-directed DNA polymerase, family B, multifunctional domain
    Interpro Name DNA-directed DNA polymerase, family B
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR006172
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    DNA REPAIR
    DRUGGABLE GENOME
    DNA DIRECTED RNA POLYMERASE
    CLINICALLY ACTIONABLE
    ENZYME
  • Interaction Score: 12.76

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18364258


    Sources:
    DTC

  • Interaction Score: 2.13

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction DNA polymerase (alpha/delta/epsilon) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 1.82

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction DNA polymerase (alpha/delta/epsilon) inhibitor

    PMIDs:
    None found


  • Interaction Score: 1.42

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction DNA polymerase (alpha/delta/epsilon) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.3

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction DNA polymerase (alpha/delta/epsilon) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    POLD1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    DPOD1_HUMAN Uniprot Id
    POLD1 Uniprot Gene Name
    DNA POLYMERASE DELTA CATALYTIC SUBUNIT Uniprot Protein Name

    Gene Info:
    Interpro Acc IPR006133
    Interpro Type Domain
    Interpro Acc IPR006134

    Gene Categories:
    DNA DIRECTED RNA POLYMERASE

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000062822 Ensembl Gene Id
    DNA POLYMERASE DELTA CATALYTIC SUBUNIT (EC 2.7.7.7) (DNA POLYMERASE DELTA SUBUNIT P125). [SOURCE:UNIPROT/SWISSPROT;ACC:P28340] Description
    POLD1 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 02-September-2020
    • Version: 31-May-2017

    Alternate Names:
    ENSG00000062822 Gene Symbol
    POLD1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    POLD GENE_SYMBOL
    POLD1 GENE_SYMBOL
    DNA polymerase delta catalytic subunit UNIPROT

    Gene Info:

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000062822 Ensembl Gene ID
    CDC2 Human Protein Atlas Gene Synonym
    POLD Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

    • Version: 11-November-2018

    Alternate Names:
    POLD1 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    POLD GO Gene Synonym

    Gene Info:

    Gene Categories:
    DNA REPAIR

    Publications:

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: