• PRKCG 5582 Druggable Genome

    Alternate Names:

    5582
    PROTEIN KINASE C GAMMA
    PRKCG
    PKC-gamma
    PKCC
    PKCG
    SCA14
    176980
    9402
    ENSG00000126583
    OTTHUMG00000064846
    1484
    P05129
    NM_002739
    NP_002730
    PKC
    PROTEIN KINASE C, GAMMA TYPE (EC 2.7.1.37) (PKC-GAMMA). [SOURCE:UNIPROT/SWISSPROT;ACC:P05129]
    Protein kinase C gamma type
    KPCG_HUMAN
    T47107
    MGC57564
    BE0009588

    Gene Info:

    GuideToPharmacology Gene Category Name Alpha subfamily
    GuideToPharmacology Gene Category ID 532
    Human Readable Name DRUGGABLE GENOME
    Initial Gene Query PKC gamma
    Counted Citations from 1950-2000 349
    Target Class Enzymes
    Target Subclass EC:2.7.11.13
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Type Domain
    Interpro Acc IPR002290
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Uniprot Status Swiss-Prot
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name KINASE
    Gene Biotype PROTEIN_CODING
    (12 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME
  • Interaction Score: 0.32

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found


  • Interaction Score: 0.28

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found


  • Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Novel drug target Established target
    Trial Name Bryostatin

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 0.17

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? True

    PMIDs:
    None found


  • Interaction Score: 0.17

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.16

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.13

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.11

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.1

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.08

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    26516587


    Sources:
    DrugBank

    • Version: 101_38

    Alternate Names:
    PRKCG Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: February-2014

    Alternate Names:
    5582 Entrez Gene ID

    Gene Info:
    Initial Gene Query PKC gamma
    Counted Citations from 1950-2000 349

    Gene Categories:
    KINASE

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    P05129 Uniprot Accession
    5582 Entrez Gene Id
    PRKCG Uniprot Gene Name

    Gene Info:
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Type Domain
    Interpro Acc IPR002290

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: January-2014

    Alternate Names:
    PRKCG Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.13

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    PROTEIN KINASE C, GAMMA TYPE (EC 2.7.1.37) (PKC-GAMMA). [SOURCE:UNIPROT/SWISSPROT;ACC:P05129] Description
    PRKCG Display Id
    ENSG00000126583 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    9402 HUGO Gene ID
    9402 HUGO Gene Symbol
    protein kinase C gamma HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Alpha subfamily
    GuideToPharmacology Gene Category ID 532

    Gene Categories:
    ENZYME

    Publications:

    • Version: 5.1.7

    Alternate Names:
    PRKCG DrugBank Gene Name
    P05129 UniProt Accession
    5582 Entrez Gene Id

    Gene Info:

    • Version: 20-Jun-2017

    Alternate Names:
    5582 Entrez Gene Id
    PRKCG MyCancerGenome Gene Symbol
    PKC-gamma MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000126583 Gene Symbol
    PRKCG Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    PKCG GENE_SYMBOL
    PRKCG GENE_SYMBOL
    Protein kinase C gamma type UNIPROT

    Gene Info:

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000126583 Ensembl Gene ID
    MGC57564 Human Protein Atlas Gene Synonym
    PKCC Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

    • Version: 03-September-2020

    Alternate Names:
    Protein kinase C gamma type Gene Name
    P05129 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

    • Version: 05-September-2020

    Alternate Names:
    PKCG GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    5582 Gene ID
    PKC-gamma dGene Synonym
    PKCC dGene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE, KINASE

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    PRKCG TTD Gene Abbreviation
    T47107 TTD Target ID

    Gene Info:

    Publications:

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: