• PRKCQ 5588 Druggable Genome

    Alternate Names:

    5588
    PROTEIN KINASE C THETA
    PRKCQ
    PRKCT
    nPKC-theta
    600448
    9410
    ENSG00000065675
    OTTHUMG00000017623
    Protein kinase C theta type
    Q04759
    KPCT_HUMAN
    PROTEIN KINASE C, THETA TYPE (EC 2.7.1.-) (NPKC-THETA). [SOURCE:UNIPROT/SWISSPROT;ACC:Q04759]
    PKC
    1488
    NP_006248
    NM_001242413
    T23995

    Gene Info:

    Target Class Enzymes
    Target Subclass EC:2.7.11.13
    Human Readable Name DRUGGABLE GENOME
    GuideToPharmacology Gene Category Name Delta subfamily
    GuideToPharmacology Gene Category ID 533
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Acc IPR002290
    Human Readable Name KINASE
    Interpro Type Domain
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Gene Biotype PROTEIN_CODING
    (9 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME
    TRANSCRIPTION FACTOR

    Publications:

  • Interaction Score: 0.34

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.31

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name Bryostatin
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 0.22

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.2

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found


  • Interaction Score: 0.19

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Protein kinase C (PKC) inhibitor

    PMIDs:
    None found


  • Interaction Score: 0.14

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Protein kinase C (PKC) inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.05

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    MyCancerGenome

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

    • Version: 101_38

    Alternate Names:
    PRKCQ Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    PROTEIN KINASE C, THETA TYPE (EC 2.7.1.-) (NPKC-THETA). [SOURCE:UNIPROT/SWISSPROT;ACC:Q04759] Description
    PRKCQ Display Id
    ENSG00000065675 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000065675 Ensembl Gene Id
    5588 Entrez Gene Id
    KPCT_HUMAN Uniprot Id

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: January-2014

    Alternate Names:
    PRKCQ Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.13

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    9410 HUGO Gene ID
    9410 HUGO Gene Symbol
    protein kinase C theta HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Delta subfamily
    GuideToPharmacology Gene Category ID 533

    Gene Categories:
    ENZYME

    Publications:

    • Version: 20-Jun-2017

    Alternate Names:
    5588 Entrez Gene Id
    PRKCQ MyCancerGenome Gene Symbol
    PKC MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000065675 Gene Symbol
    PRKCQ Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    PRKCT GENE_SYMBOL
    PRKCQ GENE_SYMBOL
    Protein kinase C theta type UNIPROT

    Gene Info:

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    5588 Gene ID
    PRKCT dGene Synonym
    nPKC-theta dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    PRKCQ TTD Gene Abbreviation
    T23995 TTD Target ID

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    PRKCT GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Protein kinase C theta type Gene Name
    Q04759 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, TRANSCRIPTION FACTOR

    Publications:

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: