DGIdb - PRLR Gene Record

PRLR 5618 Druggable Genome

Alternate Names:

5618

PROLACTIN RECEPTOR

PRLR

HPRL

MFAB

hPRLrI

176761

9446

ENSG00000113494

OTTHUMG00000090789

P16471

T26226

RI-PRLR

Gene Info:

Target Class Receptors

Target Subclass Receptor

Target Subclass Type 1 cytokine receptor

Gene Biotype PROTEIN_CODING

(3 More Sources)

Gene Categories: Category Details

CELL SURFACE

KINASE

EXTERNAL SIDE OF PLASMA MEMBRANE

DRUGGABLE GENOME

Publications:

Ormandy et al., 1992, Androgen regulation of prolactin-receptor gene expression in MCF-7 and MDA-MB-453 human breast cancer cells., Int. J. Cancer

ENDOSTATIN PRLR

Interaction Score: 20.61

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
SOMATROPIN PRLR

Interaction Score: 10.3

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name somatropin,Genotropin

Novel drug target Established target

Trial Name somatropin (intranasal)

PMIDs:
None found

Sources:
TdgClinicalTrial
ANDROSTANOLONE PRLR

Interaction Score: 1.79

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1544711

Sources:
NCI

Ensembl: ENSG00000113494
- Version: 101_38
Alternate Names:

PRLR Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
TdgClinicalTrial: P16471
- Version: January-2014
Alternate Names:

PRLR Gene Symbol

Gene Info:

Target Class Receptors

Target Subclass Receptor

Target Subclass Type 1 cytokine receptor

Publications:
NCI: PRLR
- Version: 14-September-2017
Alternate Names:

Gene Info:

Publications:

Ormandy et al., 1992, Androgen regulation of prolactin-receptor gene expression in MCF-7 and MDA-MB-453 human breast cancer cells., Int. J. Cancer
HingoraniCasas: ENSG00000113494
- Version: 31-May-2017
Alternate Names:

ENSG00000113494 Gene Symbol

PRLR Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
TTD: Prolactin receptor
- Version: 2020.06.01
Alternate Names:

PRLR TTD Gene Abbreviation

T26226 TTD Target ID

Gene Info:

Publications:
Pharos: PRLR
- Version: 01-February-2022
Alternate Names:

Prolactin receptor Gene Name

P16471 UniProt ID

Gene Info:

Gene Categories:

KINASE

Publications:
GO: PRLR
- Version: 01-February-2022
Alternate Names:

Gene Info:

Gene Categories:

CELL SURFACE, EXTERNAL SIDE OF PLASMA MEMBRANE

Publications:

Target Class	Receptors
Target Subclass	Receptor
Target Subclass	Type 1 cytokine receptor
Gene Biotype	PROTEIN_CODING

Trial Name	somatropin,Genotropin
Novel drug target	Established target
Trial Name	somatropin (intranasal)

5618
PROLACTIN RECEPTOR
PRLR
HPRL
MFAB
hPRLrI
176761
9446
ENSG00000113494
OTTHUMG00000090789
P16471
T26226
RI-PRLR

CELL SURFACE
KINASE
EXTERNAL SIDE OF PLASMA MEMBRANE
DRUGGABLE GENOME

ENSG00000113494	Gene Symbol
PRLR	Ensembl Id

PRLR	TTD Gene Abbreviation
T26226	TTD Target ID

PRLR Gene Record

PRLR 5618 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

ENDOSTATIN PRLR

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

SOMATROPIN PRLR

Interaction Types & Directionality: n/a

Interaction Info: Trial Name somatropin,Genotropin Novel drug target Established target Trial Name somatropin (intranasal)

PMIDs: None found

Sources: TdgClinicalTrial

ANDROSTANOLONE PRLR

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1544711

Sources: NCI

Ensembl: ENSG00000113494

Alternate Names: PRLR Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

TdgClinicalTrial: P16471

Alternate Names: PRLR Gene Symbol

Gene Info: Target Class Receptors Target Subclass Receptor Target Subclass Type 1 cytokine receptor

Publications:

NCI: PRLR

Alternate Names:

Gene Info:

Publications: Ormandy et al., 1992, Androgen regulation of prolactin-receptor gene expression in MCF-7 and MDA-MB-453 human breast cancer cells., Int. J. Cancer

HingoraniCasas: ENSG00000113494

Alternate Names: ENSG00000113494 Gene Symbol PRLR Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

TTD: Prolactin receptor

Alternate Names: PRLR TTD Gene Abbreviation T26226 TTD Target ID

Gene Info:

Publications:

Pharos: PRLR

Alternate Names: Prolactin receptor Gene Name P16471 UniProt ID

Gene Info:

Gene Categories: KINASE

Publications:

GO: PRLR

Alternate Names:

Gene Info:

Gene Categories: CELL SURFACE, EXTERNAL SIDE OF PLASMA MEMBRANE

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name somatropin,Genotropin

Novel drug target Established target

Trial Name somatropin (intranasal)

PMIDs:
None found

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

n/a

PMIDs:
1544711

Sources:
NCI

Alternate Names:

PRLR Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

PRLR Gene Symbol

Gene Info:

Target Class Receptors

Target Subclass Receptor

Target Subclass Type 1 cytokine receptor

Publications:

Ormandy et al., 1992, Androgen regulation of prolactin-receptor gene expression in MCF-7 and MDA-MB-453 human breast cancer cells., Int. J. Cancer

Alternate Names:

ENSG00000113494 Gene Symbol

PRLR Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

PRLR TTD Gene Abbreviation

T26226 TTD Target ID

Alternate Names:

Prolactin receptor Gene Name

P16471 UniProt ID

Gene Categories:

KINASE

Gene Categories:

CELL SURFACE, EXTERNAL SIDE OF PLASMA MEMBRANE